Literature DB >> 2334850

Quantitative analysis of glutathione in rat central nervous system: comparison of GSH in infant brain with that in adult brain.

H Kudo1, T Kokunai, T Kondoh, N Tamaki, S Matsumoto.   

Abstract

Reduced glutathione (GSH) plays an important role in cellular protection against damage from free radicals and other electrophiles. GSH in the rat central nervous system was quantitatively analyzed. In adult brain, tissue from the cerebellum and cerebrum had higher GSH levels than that from the brainstem and spinal cord. Infant cerebrum and cerebellum contained lower levels of GSH than adult cerebrum and cerebellum. These data seem to suggest that the brainstem and spinal cord in adults, and the cerebrum and cerebellum in infants, are more vulnerable to injury by free radical-like radiation than the cerebrum and cerebellum in adults.

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Year:  1990        PMID： 2334850     DOI： 10.1016/0006-8993(90)90178-e

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  6 in total

1.  A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons.

Authors:  Debolina Ghosh; Kelsey R LeVault; Aaron J Barnett; Gregory J Brewer
Journal:  J Neurosci       Date:  2012-04-25       Impact factor: 6.167

Review 2.  Edited magnetic resonance spectroscopy in the neonatal brain.

Authors:  Yulu Song; Peter J Lally; Maria Yanez Lopez; Georg Oeltzschner; Mary Beth Nebel; Borjan Gagoski; Steven Kecskemeti; Steve C N Hui; Helge J Zöllner; Deepika Shukla; Tomoki Arichi; Enrico De Vita; Vivek Yedavalli; Sudhin Thayyil; Daniele Fallin; Douglas C Dean; P Ellen Grant; Jessica L Wisnowski; Richard A E Edden
Journal:  Neuroradiology       Date:  2021-10-15       Impact factor: 2.995

Review 3.  Glucose-6-phosphate dehydrogenase expression associated with NADPH-dependent reactions in cerebellar neurons.

Authors:  Enrica Biagiotti; Loretta Guidi; Paolo Del Grande; Paolino Ninfali
Journal:  Cerebellum       Date:  2003       Impact factor: 3.847

Review 4.  Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson's Disease.

Authors:  Junjun Zhao; Shuqing Yu; Yan Zheng; Hui Yang; Jianliang Zhang
Journal:  Mol Neurobiol       Date:  2016-02-03       Impact factor: 5.590

5.  Methylmercury exposure during prenatal and postnatal neurodevelopment promotes oxidative stress associated with motor and cognitive damages in rats: an environmental-experimental toxicology study.

Authors:  Beatriz Helena Fernandes Fagundes; Priscila Cunha Nascimento; Walessa Alana Bragança Aragão; Victória Santos Chemelo; Leonardo Oliveira Bittencourt; Luciana Eiró-Quirino; Marcia Cristina Freitas Silva; Marco Aurelio M Freire; Luanna Melo Pereira Fernandes; Cristiane do Socorro Ferraz Maia; Maria Elena Crespo-Lopez; Rafael Rodrigues Lima
Journal:  Toxicol Rep       Date:  2022-02-26

6.  Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.

Authors:  K I Lin; S H Lee; R Narayanan; J M Baraban; J M Hardwick; R R Ratan
Journal:  J Cell Biol       Date:  1995-12       Impact factor: 10.539
  6 in total

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