Literature DB >> 23347944

Quality control: putting protein aggregates in a bind.

Jay R Unruh1, Brian D Slaughter, Rong Li.   

Abstract

Asymmetric inheritance of protein aggregates in budding yeast is a fascinating yet controversial area of aging research. A recent study demonstrates that unfolded protein aggregates are confined to the mother by tethering to organelles rather than retrograde transport.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23347944     DOI: 10.1016/j.cub.2012.12.005

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  3 in total

1.  Repair rather than segregation of damage is the optimal unicellular aging strategy.

Authors:  Robert J Clegg; Rosemary J Dyson; Jan-Ulrich Kreft
Journal:  BMC Biol       Date:  2014-08-16       Impact factor: 7.431

Review 2.  From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality.

Authors:  Jan-Ulrich Kreft; Caroline M Plugge; Clara Prats; Johan H J Leveau; Weiwen Zhang; Ferdi L Hellweger
Journal:  Front Microbiol       Date:  2017-11-27       Impact factor: 5.640

3.  Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice.

Authors:  Monica R P Elmore; Lindsay A Hohsfield; Enikö A Kramár; Lilach Soreq; Rafael J Lee; Stephanie T Pham; Allison R Najafi; Elizabeth E Spangenberg; Marcelo A Wood; Brian L West; Kim N Green
Journal:  Aging Cell       Date:  2018-10-02       Impact factor: 9.304

  3 in total

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