| Literature DB >> 23347063 |
Shih-Han S Huang1, Rommel G Tirona, Cameron Ross, Rita S Suri.
Abstract
Owing to the drug's favorable hydrophilic and pharmacokinetic characteristics, a number of case reports have demonstrated effective treatment of atenolol overdose with hemodialysis. However, the efficiency of atenolol clearance throughout hemodialysis treatments has not previously been examined. In this report, a patient with impaired renal function was successfully treated with two 5-hour intermittent high-flux high-efficiency hemodialysis therapies after atenolol overdose. Serial atenolol levels were measured during his hemodialysis treatments. We observed an over 50% plasma atenolol concentration reduction after each 5-hour hemodialysis therapy. Hemodialysis therapy is an effective treatment for atenolol overdose, especially in patients with impaired renal function.Entities:
Keywords: Hemodialysis; atenolol; drug intoxication; overdose
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Year: 2013 PMID: 23347063 DOI: 10.1111/hdi.12020
Source DB: PubMed Journal: Hemodial Int ISSN: 1492-7535 Impact factor: 1.812