Literature DB >> 23347063

Case report: atenolol overdose successfully treated with hemodialysis.

Shih-Han S Huang1, Rommel G Tirona, Cameron Ross, Rita S Suri.   

Abstract

Owing to the drug's favorable hydrophilic and pharmacokinetic characteristics, a number of case reports have demonstrated effective treatment of atenolol overdose with hemodialysis. However, the efficiency of atenolol clearance throughout hemodialysis treatments has not previously been examined. In this report, a patient with impaired renal function was successfully treated with two 5-hour intermittent high-flux high-efficiency hemodialysis therapies after atenolol overdose. Serial atenolol levels were measured during his hemodialysis treatments. We observed an over 50% plasma atenolol concentration reduction after each 5-hour hemodialysis therapy. Hemodialysis therapy is an effective treatment for atenolol overdose, especially in patients with impaired renal function.
© 2013 The Authors. Hemodialysis International © 2013 International Society for Hemodialysis.

Entities:  

Keywords:  Hemodialysis; atenolol; drug intoxication; overdose

Mesh:

Substances:

Year:  2013        PMID: 23347063     DOI: 10.1111/hdi.12020

Source DB:  PubMed          Journal:  Hemodial Int        ISSN: 1492-7535            Impact factor:   1.812


  4 in total

1.  Massive Atenolol, Lisinopril, and Chlorthalidone Overdose Treated with Endoscopic Decontamination, Hemodialysis, Impella Percutaneous Left Ventricular Assist Device, and ECMO.

Authors:  C William Heise; David Beutler; Adam Bosak; Geoffrey Orme; Akil Loli; Kimberlie Graeme
Journal:  J Med Toxicol       Date:  2015-03

2.  β-Blocker Dialyzability in Maintenance Hemodialysis Patients: A Randomized Clinical Trial.

Authors:  Alvin Tieu; Thomas J Velenosi; Andrew S Kucey; Matthew A Weir; Bradley L Urquhart
Journal:  Clin J Am Soc Nephrol       Date:  2018-03-08       Impact factor: 8.237

Review 3.  The Role of Renal Replacement Therapy in the Management of Pharmacologic Poisonings.

Authors:  Aibek E Mirrakhimov; Aram Barbaryan; Adam Gray; Taha Ayach
Journal:  Int J Nephrol       Date:  2016-11-30

4.  Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup.

Authors:  Josée Bouchard; Greene Shepherd; Robert S Hoffman; Sophie Gosselin; Darren M Roberts; Yi Li; Thomas D Nolin; Valéry Lavergne; Marc Ghannoum
Journal:  Crit Care       Date:  2021-06-10       Impact factor: 9.097

  4 in total

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