Literature DB >> 2334635

Infant acute lymphoblastic leukaemia with t(11; 19).

B Gibbons1, F E Katz, P Ganly, J M Chessells.   

Abstract

Seven cases of infant acute lymphoblastic leukaemia with t(11; 19) (q23; p13) are described. They are characterized by a high white cell count, organomegaly, early central nervous system (CNS) disease, and a poor prognosis. Blasts are usually of an immature early B-cell lineage although monocytoid features are present in some cases. The characteristics of infant acute leukaemia with t(11; 19) are very similar to those found with t(4; 11), and the presence of t(11; 19) may indicate the same poor prognosis.

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Year:  1990        PMID： 2334635     DOI： 10.1111/j.1365-2141.1990.tb02581.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


  6 in total

1.  Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

Authors:  J Corral; A Forster; S Thompson; F Lampert; Y Kaneko; R Slater; W G Kroes; C E van der Schoot; W D Ludwig; A Karpas
Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-15       Impact factor: 11.205

2.  Cytogenetic findings in acute leukaemias of infants.

Authors:  F Lampert; J Harbott; J Ritterbach
Journal:  Br J Cancer Suppl       Date:  1992-08

3.  Structure and expression of the human trithorax-like gene 1 involved in acute leukemias.

Authors:  P Parry; M Djabali; M Bower; J Khristich; M Waterman; B Gibbons; B D Young; G Evans
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-15       Impact factor: 11.205

4.  Chromosomes in childhood acute lymphoblastic leukaemia: karyotypic patterns in disease subtypes.

Authors:  M A Wodzinski; A E Watmore; J S Lilleyman; A M Potter
Journal:  J Clin Pathol       Date:  1991-01       Impact factor: 3.411

5.  Stem cell origins of leukaemia and curability.

Authors:  M F Greaves
Journal:  Br J Cancer       Date:  1993-03       Impact factor: 7.640

6.  Molecular cloning of 19p13 breakpoint region in infantile leukemia with t(11;19)(q23;p13) translocation.

Authors:  S Iida; M Seto; K Yamamoto; H Komatsu; Y Akao; S Nakazawa; Y Ariyoshi; T Takahashi; R Ueda
Journal:  Jpn J Cancer Res       Date:  1993-05
  6 in total

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