Literature DB >> 23345257

Biomechanical responses of a pig head under blast loading: a computational simulation.

Feng Zhu1, Paul Skelton, Cliff C Chou, Haojie Mao, King H Yang, Albert I King.   

Abstract

A series of computational studies were performed to investigate the biomechanical responses of the pig head under a specific shock tube environment. A finite element model of the head of a 50-kg Yorkshire pig was developed with sufficient details, based on the Lagrangian formulation, and a shock tube model was developed using the multimaterial arbitrary Lagrangian-Eulerian (MMALE) approach. These two models were integrated and a fluid/solid coupling algorithm was used to simulate the interaction of the shock wave with the pig's head. The finite element model-predicted incident and intracranial pressure traces were in reasonable agreement with those obtained experimentally. Using the verified numerical model of the shock tube and pig head, further investigations were carried out to study the spatial and temporal distributions of pressure, shear stress, and principal strain within the head. Pressure enhancement was found in the skull, which is believed to be caused by shock wave reflection at the interface of the materials with distinct wave impedances. Brain tissue has a shock attenuation effect and larger pressures were observed in the frontal and occipital regions, suggesting a greater possibility of coup and contrecoup contusion. Shear stresses in the brain and deflection in the skull remained at a low level. Higher principal strains were observed in the brain near the foramen magnum, suggesting that there is a greater chance of cellular or vascular injuries in the brainstem region.
Copyright © 2012 John Wiley & Sons, Ltd.

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Mesh:

Year:  2012        PMID: 23345257     DOI: 10.1002/cnm.2518

Source DB:  PubMed          Journal:  Int J Numer Method Biomed Eng        ISSN: 2040-7939            Impact factor:   2.747


  12 in total

Review 1.  The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden.

Authors:  David F Meaney; Barclay Morrison; Cameron Dale Bass
Journal:  J Biomech Eng       Date:  2014-02       Impact factor: 2.097

2.  Modeling the Long-Term Consequences of Repeated Blast-Induced Mild Traumatic Brain Injuries.

Authors:  Denes V Agoston
Journal:  J Neurotrauma       Date:  2017-09       Impact factor: 5.269

3.  Blast Scaling Parameters: Transitioning from Lung to Skull Base Metrics.

Authors:  Brandon P Lucke-Wold; Ryan C Turner; Aric Flint Logsdon; Charles L Rosen; Rabia Qaiser
Journal:  J Surg Emerg Med       Date:  2017-01-10

4.  Computational simulation of the mechanical response of brain tissue under blast loading.

Authors:  Kaveh Laksari; Soroush Assari; Benjamin Seibold; Keya Sadeghipour; Kurosh Darvish
Journal:  Biomech Model Mechanobiol       Date:  2014-09-10

Review 5.  Animal models of traumatic brain injury: a review of pathophysiology to biomarkers and treatments.

Authors:  Abigail Petersen; Matthew Soderstrom; Biswajit Saha; Pushpa Sharma
Journal:  Exp Brain Res       Date:  2021-07-29       Impact factor: 1.972

Review 6.  When physics meets biology: low and high-velocity penetration, blunt impact, and blast injuries to the brain.

Authors:  Leanne Young; Gregory T Rule; Robert T Bocchieri; Timothy J Walilko; Jennie M Burns; Geoffrey Ling
Journal:  Front Neurol       Date:  2015-05-07       Impact factor: 4.003

7.  Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms.

Authors:  Aric Flint Logsdon; Ryan Coddington Turner; Brandon Peter Lucke-Wold; Matthew James Robson; Zachary James Naser; Kelly Elizabeth Smith; Rae Reiko Matsumoto; Jason Delwyn Huber; Charles Lee Rosen
Journal:  Front Cell Neurosci       Date:  2014-12-10       Impact factor: 5.505

Review 8.  Considerations for Experimental Animal Models of Concussion, Traumatic Brain Injury, and Chronic Traumatic Encephalopathy-These Matters Matter.

Authors:  Mark W Wojnarowicz; Andrew M Fisher; Olga Minaeva; Lee E Goldstein
Journal:  Front Neurol       Date:  2017-06-01       Impact factor: 4.003

9.  Mathematical Models of Blast-Induced TBI: Current Status, Challenges, and Prospects.

Authors:  Raj K Gupta; Andrzej Przekwas
Journal:  Front Neurol       Date:  2013-05-30       Impact factor: 4.003

10.  Biomechanical Responses of the Brain in Swine Subject to Free-Field Blasts.

Authors:  Ke Feng; Liying Zhang; Xin Jin; Chaoyang Chen; Srinivasu Kallakuri; Tal Saif; John Cavanaugh; Albert King
Journal:  Front Neurol       Date:  2016-10-24       Impact factor: 4.003

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