Ahmet Kaya1, Mustafa Kurt2, Ibrahim Halil Tanboga3, Turgay Işık2, Zeki Yüksel Günaydın4, Yasemin Kaya5, Selim Topçu3, Serdar Sevimli3. 1. Department of Cardiology, Ordu University Medical School, Ordu, Turkey drkayaahmet@yahoo.com. 2. Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey. 3. Department of Cardiology, Ataturk University Medical School, Erzurum, Turkey. 4. Department of Cardiology, Ordu University Medical School, Ordu, Turkey. 5. Internal Medicine, Erzurum Education and Research Hospital, Erzurum, Turkey.
Abstract
OBJECTIVES: We examined the association between neutrophil to lymphocyte ratio (NLR) and the complexity of coronary artery disease assessed by SYNTAX score (SS). METHODS: The study population included patients with chest pain who had undergone coronary angiography for stable angina pectoris. Patients were classified depending on whether the SS was 0 or SS > 0. RESULTS: Left ventricular ejection fraction, estimated glomerular filtration rate, and NLR were found to be the independent predictors of high SS in multivariate analysis. The area under the receiver-operating curve of NLR was 0.72 (0.65-0.80, P < .001) for predicting high SS. The optimal cutoff value of NLR to predict high SS was 2.7 (sensitivity of 72% and a specificity of 61%). There was a significant correlation between NLR ratio and continuous SS (r = .552, P < .001). CONCLUSION: The NLR is a readily measurable systemic inflammatory marker and is associated with both the presence and the complexity of coronary artery disease.
OBJECTIVES: We examined the association between neutrophil to lymphocyte ratio (NLR) and the complexity of coronary artery disease assessed by SYNTAX score (SS). METHODS: The study population included patients with chest pain who had undergone coronary angiography for stable angina pectoris. Patients were classified depending on whether the SS was 0 or SS > 0. RESULTS: Left ventricular ejection fraction, estimated glomerular filtration rate, and NLR were found to be the independent predictors of high SS in multivariate analysis. The area under the receiver-operating curve of NLR was 0.72 (0.65-0.80, P < .001) for predicting high SS. The optimal cutoff value of NLR to predict high SS was 2.7 (sensitivity of 72% and a specificity of 61%). There was a significant correlation between NLR ratio and continuous SS (r = .552, P < .001). CONCLUSION: The NLR is a readily measurable systemic inflammatory marker and is associated with both the presence and the complexity of coronary artery disease.
Authors: Emin Murat Akbas; Levent Demirtas; Adalet Ozcicek; Aysu Timuroglu; Eftal Murat Bakirci; Hikmet Hamur; Fatih Ozcicek; Kultigin Turkmen Journal: Int J Clin Exp Med Date: 2014-07-15
Authors: Levent Demirtas; Husnu Degirmenci; Emin Murat Akbas; Adalet Ozcicek; Aysu Timuroglu; Ali Gurel; Fatih Ozcicek Journal: Int J Clin Exp Med Date: 2015-07-15