Functional outcome after liver transplantation: a preliminary report.

Although the number of patients undergoing successful liver transplants each year has increased dramatically, little information is available on the functional outcome of such patients. A survey was conducted to determine the functional and vocational outcome of patients three years after orthotopic liver transplantation. Questionnaires were sent to 45 patients who had liver transplants in 1985, of whom 31 responded. Fourteen patients (47%) reported abnormal function in at least one limb; four patients (13%) reported developing gout. All patients were independent in ADLs and mobility; assistive devices were used by four patients. Nineteen patients (61%) reported severe impairment in endurance before transplant; 15 (48%) were unable to ambulate outside the house. After transplant only two patients (6%) reported severely impaired endurance, and all but two were able to walk at least three blocks. Three years after transplant, 12 patients (39%) were working full time and eight patients (26%) were homemakers. Work performance was most commonly limited by fractures (12 patients) and lack of concentration (seven patients). Thus, despite frequent limitations in limb function, patients after liver transplant are largely independent in ADLs and mobility, have improved endurance, and can often return to work despite physical limitations.