Literature DB >> 2334214

Acute liver failure induced by carbamazepine.

N Hadzić1, B Portmann, E T Davies, A P Mowat, G Mieli-Vergani.   

Abstract

Two children developed acute liver failure while taking carbamazepine. Clinical and laboratory findings suggested an immunoallergic reaction, but only one child improved on steroids. Determination of liver function during the first few weeks of treatment and early detection of signs of idiosyncrasy may prevent this rare but severe complication.

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Year:  1990        PMID: 2334214      PMCID: PMC1792290          DOI: 10.1136/adc.65.3.315

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  5 in total

1.  Fatal carbamazepine hepatitis.

Authors:  P Zucker; F Daum; M I Cohen
Journal:  J Pediatr       Date:  1977-10       Impact factor: 4.406

Review 2.  Carbamazepine side effects in children and adults.

Authors:  J M Pellock
Journal:  Epilepsia       Date:  1987       Impact factor: 5.864

3.  Fatal hepatic necrosis associated with multiple anticonvulsant therapy.

Authors:  D W Smith; G J Cullity; E P Silberstein
Journal:  Aust N Z J Med       Date:  1988-06

4.  Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.

Authors:  N H Shear; S P Spielberg
Journal:  J Clin Invest       Date:  1988-12       Impact factor: 14.808

Review 5.  Hepatotoxic reactions associated with carbamazepine therapy.

Authors:  S Horowitz; R Patwardhan; E Marcus
Journal:  Epilepsia       Date:  1988 Mar-Apr       Impact factor: 5.864

  5 in total
  2 in total

1.  Hepatorenal failure after carbamazepine therapy.

Authors:  N Hadzić
Journal:  Eur J Pediatr       Date:  1993-07       Impact factor: 3.183

Review 2.  Immunological adverse effects of anticonvulsants. What is their clinical relevance?

Authors:  F De Ponti; S Lecchini; M Cosentino; C M Castelletti; A Malesci; G M Frigo
Journal:  Drug Saf       Date:  1993-03       Impact factor: 5.606

  2 in total

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