Literature DB >> 2334201

UKALL X--an effective treatment for stage III mediastinal non-Hodgkin's lymphoma.

K Wheeler1, J M Chessells.   

Abstract

Fifteen children with mediastinal non-Hodgkin's lymphoma were treated with MRC UKALL X, the current national protocol for acute lymphoblastic leukaemia. The treatment was well tolerated, and in a minimum follow up period of 46 months the event free survival of 93% was significantly better than that in a group of historical controls treated with intermittent chemotherapy regimens whose survival was only 57%. We conclude that intensive induction and consolidation treatment, with continued oral drugs, provides an effective approach to the management of mediastinal non-Hodgkin's lymphoma.

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Year:  1990        PMID： 2334201      PMCID： PMC1792248          DOI： 10.1136/adc.65.3.252

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  6 in total

1.  Childhood non-Hodgkin's lymphoma. The results of a randomized therapeutic trial comparing a 4-drug regimen (COMP) with a 10-drug regimen (LSA2-L2).

Authors:  J R Anderson; J F Wilson; D T Jenkin; A T Meadows; J Kersey; R R Chilcote; P Coccia; P Exelby; J Kushner; S Siegel; D Hammond
Journal:  N Engl J Med       Date:  1983-03-10       Impact factor: 91.245

2.  A novel treatment of childhood lymphoblastic non-Hodgkin's lymphoma: early and intermittent use of teniposide plus cytarabine.

Authors:  G V Dahl; G Rivera; C H Pui; J Mirro; J Ochs; D K Kalwinsky; M Abromowitch; A T Look; S B Murphy
Journal:  Blood       Date:  1985-11       Impact factor: 22.113

3.  Intensive consolidation chemotherapy for acute lymphoblastic leukaemia (UKALL X pilot study).

Authors:  C R Pinkerton; A Bowman; H Holtzel; J M Chessells
Journal:  Arch Dis Child       Date:  1987-01       Impact factor: 3.791

4.  Non-Hodgkin's lymphoma in children: a progress report on the original patients treated with the LSA2-L2 protocol.

Authors:  N Wollner; P R Exelby; P H Lieberman
Journal:  Cancer       Date:  1979-12       Impact factor: 6.860

5.  Adjuvant low dose radiation in childhood T cell leukaemia/lymphoma (report from the United Kingdom Childrens' Cancer Study Group--UKCCSG).

Authors:  M G Mott; J M Chessells; M L Willoughby; J R Mann; P H Morris-Jones; J S Malpas; M K Palmer
Journal:  Br J Cancer       Date:  1984-10       Impact factor: 7.640

6.  Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples.

Authors:  R Peto; M C Pike; P Armitage; N E Breslow; D R Cox; S V Howard; N Mantel; K McPherson; J Peto; P G Smith
Journal:  Br J Cancer       Date:  1977-01       Impact factor: 7.640
  6 in total

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