Literature DB >> 23340605

Cationic arene ruthenium(II) complexes with chelating P-functionalized alkyl phenyl sulfide and sulfoxide ligands as potent anticancer agents.

Gerd Ludwig1, Goran N Kaluđerović, Tobias Rüffer, Martin Bette, Marcus Korb, Michael Block, Reinhard Paschke, Heinrich Lang, Dirk Steinborn.   

Abstract

The synthesis and characterization of cationic ruthenium(II) complexes of the type [Ru(η(6)-p-cym)Cl{Ph(2)P(CH(2))(n)S(O)(x)Ph-κP,κS}][PF(6)] (n = 1-3; x = 0, 1; p-cym = p-cymene) are presented. Furthermore, their high biological potential even against cisplatin-resistant tumor cell lines and their structure-activity relationships are discussed.

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Year:  2013        PMID： 23340605     DOI： 10.1039/c3dt33064h

Source DB:  PubMed          Journal:  Dalton Trans        ISSN： 1477-9226            Impact factor:   4.390


  3 in total

1.  In vitro effects of binuclear (η (6)-p-cymene)ruthenium(II) complex containing bridging bis(nicotinate)-polyethylene glycol ester ligand on differentiation pathways of murine Th lymphocytes activated by T cell mitogen.

Authors:  Miljana Momcilovic; Thomas Eichhorn; Jana Blazevski; Harry Schmidt; Goran N Kaluđerović; Stanislava Stosic-Grujicic
Journal:  J Biol Inorg Chem       Date:  2015-02-10       Impact factor: 3.358

2.  Arene Ruthenium(II) Complexes Bearing the κ-P or κ-P,κ-S Ph2P(CH2)3SPh Ligand.

Authors:  Sören Arlt; Vladana Petković; Gerd Ludwig; Thomas Eichhorn; Heinrich Lang; Tobias Rüffer; Sanja Mijatović; Danijela Maksimović-Ivanić; Goran N Kaluđerović
Journal:  Molecules       Date:  2021-03-25       Impact factor: 4.411

3.  pH-Responsive Release of Ruthenium Metallotherapeutics from Mesoporous Silica-Based Nanocarriers.

Authors:  Minja Mladenović; Ibrahim Morgan; Nebojša Ilić; Mohamad Saoud; Marija V Pergal; Goran N Kaluđerović; Nikola Ž Knežević
Journal:  Pharmaceutics       Date:  2021-03-28       Impact factor: 6.321
  3 in total

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