Eccentric inorganic-polymeric nanoparticles formation by thermal induced cross-linked esterification and conversion of eccentricity to raspberry-like Janus.

The thermally induced cross-linked esterification occurs for the formation of eccentric inorganic-polymeric nanoparticles. By taking advantage of eccentricity, Ag-PSMA eccentric structure is converted to raspberry-like Au-based Janus nanoparticles.