PURPOSE OF REVIEW: To review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation. RECENT FINDINGS: Even with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation. SUMMARY: Measure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies.
PURPOSE OF REVIEW: To review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation. RECENT FINDINGS: Even with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation. SUMMARY: Measure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies.
Authors: Prateeti Khazanie; Bradley G Hammill; Chetan B Patel; Michael S Kiernan; Lauren B Cooper; Suzanne V Arnold; Timothy J Fendler; John A Spertus; Lesley H Curtis; Adrian F Hernandez Journal: J Card Fail Date: 2016-02-15 Impact factor: 5.712
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Authors: Brian A Houston; Rohan J Kalathiya; Steven Hsu; Rahul Loungani; Mary E Davis; Samuel T Coffin; Nicholas Haglund; Simon Maltais; Mary E Keebler; Peter J Leary; Daniel P Judge; Gerin R Stevens; John Rickard; Chris M Sciortino; Glenn J Whitman; Ashish S Shah; Stuart D Russell; Ryan J Tedford Journal: J Heart Lung Transplant Date: 2016-02-09 Impact factor: 10.247