Literature DB >> 23337815

Review of drugs for Alzheimer's disease.

Xiaoting Sun1, Lan Jin, Peixue Ling.   

Abstract

Alzheimer's disease (AD) is the most common form of dementia in the elderly. The number of people affected by AD is rapidly increasing. AD is characterized by cerebral atrophy, cerebral senile plaques, intraneuronal neurofibrillary tangles, and neuronal cell loss. Medical treatment of AD has a long history and differing results. We will review the effectiveness and limitations of the drugs used to treat AD.

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Year:  2012        PMID： 23337815

Source DB:  PubMed          Journal:  Drug Discov Ther        ISSN： 1881-7831


  22 in total

1.  Cdk5-Foxo3 axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models.

Authors:  Chun Shi; Keith Viccaro; Hyoung-Gon Lee; Kavita Shah
Journal:  J Cell Sci       Date:  2016-03-09       Impact factor: 5.285

2.  The Cdk5-Mcl-1 axis promotes mitochondrial dysfunction and neurodegeneration in a model of Alzheimer's disease.

Authors:  Kumar Nikhil; Kavita Shah
Journal:  J Cell Sci       Date:  2017-07-27       Impact factor: 5.285

3.  Does caffeine influence the anticholinesterase and antioxidant properties of donepezil? Evidence from in vitro and in vivo studies.

Authors:  Ganiyu Oboh; Opeyemi Babatunde Ogunsuyi; Oluwaseyi Emmanuel Olonisola
Journal:  Metab Brain Dis       Date:  2017-01-13       Impact factor: 3.584

Review 4.  Research progress on flavonoids isolated from traditional Chinese medicine in treatment of Alzheimer's disease.

Authors:  Jianjun Gao; Yoshinori Inagaki; Yang Liu
Journal:  Intractable Rare Dis Res       Date:  2013-02

5.  Nicotine promotes the utility of short-term memory during visual search in macaque monkeys.

Authors:  Ryo Sawagashira; Masaki Tanaka
Journal:  Psychopharmacology (Berl)       Date:  2022-07-08       Impact factor: 4.415

Review 6.  Modulation of Inflammatory Mediators and Microglial Activation Through Physical Exercise in Alzheimer's and Parkinson's Diseases.

Authors:  Erin John Rieger de Almeida; Hélio Jungkenn Ibrahim; Maria Rosa Chitolina Schetinger; Cinthia Melazzo de Andrade; Andréia Machado Cardoso
Journal:  Neurochem Res       Date:  2022-08-13       Impact factor: 4.414

7.  In silico and in vitro anti-AChE activity investigations of constituents from Mytragyna speciosa for Alzheimer's disease treatment.

Authors:  Wansiri Innok; Asadhawut Hiranrat; Netnapa Chana; Thanyada Rungrotmongkol; Panita Kongsune
Journal:  J Comput Aided Mol Des       Date:  2021-01-13       Impact factor: 3.686

8.  The Synergistic Beneficial Effects of Ginkgo Flavonoid and Coriolus versicolor Polysaccharide for Memory Improvements in a Mouse Model of Dementia.

Authors:  Xianying Fang; Yan Jiang; Hui Ji; Linguo Zhao; Wei Xiao; Zhenzhong Wang; Gang Ding
Journal:  Evid Based Complement Alternat Med       Date:  2015-03-02       Impact factor: 2.629

9.  Clinical management and associated costs for moderate and severe Alzheimer's disease in urban China: a Delphi panel study.

Authors:  Xin Yu; Shengdi Chen; Xiaochun Chen; Jianjun Jia; Chunhou Li; Cong Liu; Mondher Toumi; Dominique Milea
Journal:  Transl Neurodegener       Date:  2015-08-20       Impact factor: 8.014

10.  Identification of myo-inositol hexakisphosphate (IP6) as a β-secretase 1 (BACE1) inhibitory molecule in rice grain extract and digest.

Authors:  Takako K Abe; Masayuki Taniguchi
Journal:  FEBS Open Bio       Date:  2014-01-31       Impact factor: 2.693
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