Literature DB >> 23337455

[Post-Intensive Care Unit mortality and related prognostic factors in a cohort of critically ill patients with multi-organ dysfunction].

Victoria A Hortigüela-Martín1, Marcelino Sanchez-Casado, Sancho Rodríguez-Villar, Manuel Quintana-Díaz, Carlos Marco-Schulke, Vicente Gómez-Tello, Henar Cabezas Martín, Maria Ángeles Arrese-Cosculluela.   

Abstract

BACKGROUND AND
OBJECTIVE: To assess the post-Intensive Care Unit (ICU) mortality (in-hospital and one year after hospital discharge) and the associated factors. PATIENTS AND
METHOD: Cohort design in medical-surgical patients with multi-organ dysfunction syndrome (MODS) during the first 24h of admission to ICU. We recorded the following data: personal background, functional general situation, general information about admission to ICU, hospital stay and contact by phone after one year of hospital discharge. We registered mortality at the follow-up at anytime. Cox regression was performed to evaluate mortality factors.
RESULTS: Five hundred and forty five patients were recruited. During the study period 256 patients (52.9%) died; out of them 29.5% in ICU; 14.8% of 384 patients transferred to the ward died. Of 327 discharged patients, 266 (81.3%) were contacted; 14.3% of those had died. In-hospital death-related factors were age (odds ratio [OR] 1.04; 95% confidence interval [95% CI] 1.02-1.06; P<.01) and a decreased functional general status (OR 1.7; 95% CI 1.1-2.9; P<.05). Post-hospitalisation mortality-related variables were: diminished functional general status (OR 2.42; 95% CI 1.23-4.75; P<.01) and readmission after discharge from hospital (1.45 OR; 95% CI 1.19-1.76; P<.001).
CONCLUSIONS: Patients admitted for a medical-surgical MODS presented a mortality of 52.9% within one year. The factors influencing hospital mortality are age and a generally diminished functional status, both being not modifiable factors. After discharge, the decreased general functional status remained central along with the re-hospitalisation.
Copyright © 2012 Elsevier España, S.L. All rights reserved.

Entities:  

Mesh:

Year:  2013        PMID: 23337455     DOI: 10.1016/j.medcli.2012.09.043

Source DB:  PubMed          Journal:  Med Clin (Barc)        ISSN: 0025-7753            Impact factor:   1.725


  1 in total

1.  Clinical Utility of a Structured Program to Reduce the Risk of Health-Related Quality of Life Impairment after Discharge from Intensive Care Unit: A Real-World Experience.

Authors:  Angelica Venni; Francesca Ioia; Silvia Laviola; Francesca Frigieri; Alessandra Pieri; Simona Marilli; Daniela Balzi; Piercarlo Ballo; Stefano Gori; Diletta Guarducci
Journal:  Crit Care Res Pract       Date:  2018-05-08
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.