| Literature DB >> 23336662 |
Flora Zagouri1, Dimosthenis T Chrysikos, Theodoros N Sergentanis, Georgia Giannakopoulou, Constantine G Zografos, Christos A Papadimitriou, George C Zografos.
Abstract
The main indication of prophylactic mastectomy pertains to BRCA1 or BRCA2 mutation carriers. Prophylactic mastectomy includes the simple method and the subcutaneous method. Both methods can be followed by breast plastic reconstruction either at the same time or later. This review examines key issues regarding prophylactic mastectomy: the selection of patients, its effectiveness, its limitations, convergence/divergence in existing guidelines, and future perspectives.Entities:
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Year: 2013 PMID： 23336662
Source DB: PubMed Journal: Am Surg ISSN： 0003-1348 Impact factor: 0.688