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Literature DB >> 23334826

Noncanonical NFATc1 activation in DN thymocytes.

Fernando Macian.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2013 PMID： 23334826 DOI： 10.1038/ni.2522

Source DB: PubMed Journal: Nat Immunol ISSN： 1529-2908 Impact factor: 25.606

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12 in total

1. Calcineurin B1 is essential for positive but not negative selection during thymocyte development.

Authors: Joel R Neilson; Monte M Winslow; Eun Mi Hur; Gerald R Crabtree
Journal: Immunity Date: 2004-03 Impact factor: 31.745

Review 2. NFAT proteins: key regulators of T-cell development and function.

Authors: Fernando Macian
Journal: Nat Rev Immunol Date: 2005-06 Impact factor: 53.106

3. Stat5a/b are essential for normal lymphoid development and differentiation.

Authors: Zhengju Yao; Yongzhi Cui; Wendy T Watford; Jay H Bream; Kunihiro Yamaoka; Bruce D Hissong; Denise Li; Scott K Durum; Qiong Jiang; Avinash Bhandoola; Lothar Hennighausen; John J O'Shea
Journal: Proc Natl Acad Sci U S A Date: 2006-01-17 Impact factor: 11.205

4. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc.

Authors: A M Ranger; M R Hodge; E M Gravallese; M Oukka; L Davidson; F W Alt; F C de la Brousse; T Hoey; M Grusby; L H Glimcher
Journal: Immunity Date: 1998-01 Impact factor: 31.745

5. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice.

Authors: K Akashi; M Kondo; U von Freeden-Jeffry; R Murray; I L Weissman
Journal: Cell Date: 1997-06-27 Impact factor: 41.582

6. Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity.

Authors: H Okamura; J Aramburu; C García-Rodríguez; J P Viola; A Raghavan; M Tahiliani; X Zhang; J Qin; P G Hogan; A Rao
Journal: Mol Cell Date: 2000-09 Impact factor: 17.970

Noncanonical NFATc1 activation in DN thymocytes.

1. Calcineurin B1 is essential for positive but not negative selection during thymocyte development.

Review 2. NFAT proteins: key regulators of T-cell development and function.

3. Stat5a/b are essential for normal lymphoid development and differentiation.

4. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc.

5. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice.

6. Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity.

7. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun.

8. Defective T cell development and function in calcineurin A beta -deficient mice.

9. The transcription factor NFAT4 is involved in the generation and survival of T cells.

10. An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development.

Review 1. Transcriptional Regulation of Early T-Lymphocyte Development in Thymus.