Literature DB >> 23334453

[Genetics of ischemic stroke].

A Gschwendtner1, M Dichgans.   

Abstract

Stroke is one of the most widespread causes of mortality und disability worldwide. Around 80 % of strokes are ischemic and different forms of intracranial bleeding account for the remaining cases. Monogenic stroke disorders are rare but the diagnosis may lead to specific therapeutic consequences for the affected patients who are predominantly young. In common sporadic stroke, genetic factors play a role in the form of susceptibility genes. Their discovery may give rise to new therapeutic options in the future.

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Year:  2013        PMID: 23334453     DOI: 10.1007/s00115-012-3641-3

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  29 in total

1.  A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.

Authors:  Michiaki Kubo; Jun Hata; Toshiharu Ninomiya; Koichi Matsuda; Koji Yonemoto; Toshiaki Nakano; Tomonaga Matsushita; Keiko Yamazaki; Yozo Ohnishi; Susumu Saito; Takanari Kitazono; Setsuro Ibayashi; Katsuo Sueishi; Mitsuo Iida; Yusuke Nakamura; Yutaka Kiyohara
Journal:  Nat Genet       Date:  2007-01-07       Impact factor: 38.330

2.  A common variant on chromosome 9p21 affects the risk of myocardial infarction.

Authors:  Anna Helgadottir; Gudmar Thorleifsson; Andrei Manolescu; Solveig Gretarsdottir; Thorarinn Blondal; Aslaug Jonasdottir; Adalbjorg Jonasdottir; Asgeir Sigurdsson; Adam Baker; Arnar Palsson; Gisli Masson; Daniel F Gudbjartsson; Kristinn P Magnusson; Karl Andersen; Allan I Levey; Valgerdur M Backman; Sigurborg Matthiasdottir; Thorbjorg Jonsdottir; Stefan Palsson; Helga Einarsdottir; Steinunn Gunnarsdottir; Arnaldur Gylfason; Viola Vaccarino; W Craig Hooper; Muredach P Reilly; Christopher B Granger; Harland Austin; Daniel J Rader; Svati H Shah; Arshed A Quyyumi; Jeffrey R Gulcher; Gudmundur Thorgeirsson; Unnur Thorsteinsdottir; Augustine Kong; Kari Stefansson
Journal:  Science       Date:  2007-05-03       Impact factor: 47.728

Review 3.  Inherited metabolic disorders and stroke part 1: Fabry disease and mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes.

Authors:  Fernando D Testai; Philip B Gorelick
Journal:  Arch Neurol       Date:  2010-01

Review 4.  Clinical spectrum of type IV collagen (COL4A1) mutations: a novel genetic multisystem disease.

Authors:  Katayoun Vahedi; Sonia Alamowitch
Journal:  Curr Opin Neurol       Date:  2011-02       Impact factor: 5.710

5.  Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

Authors:  Solveig Gretarsdottir; Gudmar Thorleifsson; Andrei Manolescu; Unnur Styrkarsdottir; Anna Helgadottir; Andreas Gschwendtner; Konstantinos Kostulas; Gregor Kuhlenbäumer; Steve Bevan; Thorbjorg Jonsdottir; Hjordis Bjarnason; Jona Saemundsdottir; Stefan Palsson; David O Arnar; Hilma Holm; Gudmundur Thorgeirsson; Einar Mar Valdimarsson; Sigurlaug Sveinbjörnsdottir; Christian Gieger; Klaus Berger; H-Erich Wichmann; Jan Hillert; Hugh Markus; Jeffrey Robert Gulcher; E Bernd Ringelstein; Augustine Kong; Martin Dichgans; Daniel Fannar Gudbjartsson; Unnur Thorsteinsdottir; Kari Stefansson
Journal:  Ann Neurol       Date:  2008-10       Impact factor: 10.422

6.  Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice.

Authors:  Axel Visel; Yiwen Zhu; Dalit May; Veena Afzal; Elaine Gong; Catia Attanasio; Matthew J Blow; Jonathan C Cohen; Edward M Rubin; Len A Pennacchio
Journal:  Nature       Date:  2010-02-21       Impact factor: 49.962

7.  Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke.

Authors:  Andreas Gschwendtner; Steve Bevan; John W Cole; Anna Plourde; Mar Matarin; Helen Ross-Adams; Thomas Meitinger; Erich Wichmann; Braxton D Mitchell; Karen Furie; Agnieszka Slowik; Stephen S Rich; Paul D Syme; Mary J MacLeod; James F Meschia; Jonathan Rosand; Steve J Kittner; Hugh S Markus; Bertram Müller-Myhsok; Martin Dichgans
Journal:  Ann Neurol       Date:  2009-05       Impact factor: 10.422

8.  Genomewide association studies of stroke.

Authors:  M Arfan Ikram; Sudha Seshadri; Joshua C Bis; Myriam Fornage; Anita L DeStefano; Yurii S Aulchenko; Stephanie Debette; Thomas Lumley; Aaron R Folsom; Evita G van den Herik; Michiel J Bos; Alexa Beiser; Mary Cushman; Lenore J Launer; Eyal Shahar; Maksim Struchalin; Yangchun Du; Nicole L Glazer; Wayne D Rosamond; Fernando Rivadeneira; Margaret Kelly-Hayes; Oscar L Lopez; Josef Coresh; Albert Hofman; Charles DeCarli; Susan R Heckbert; Peter J Koudstaal; Qiong Yang; Nicholas L Smith; Carlos S Kase; Kenneth Rice; Talin Haritunians; Gerwin Roks; Paul L M de Kort; Kent D Taylor; Lonneke M de Lau; Ben A Oostra; Andre G Uitterlinden; Jerome I Rotter; Eric Boerwinkle; Bruce M Psaty; Thomas H Mosley; Cornelia M van Duijn; Monique M B Breteler; W T Longstreth; Philip A Wolf
Journal:  N Engl J Med       Date:  2009-04-15       Impact factor: 91.245

9.  Hereditary connective tissue diseases in young adult stroke: a comprehensive synthesis.

Authors:  Olivier M Vanakker; Dimitri Hemelsoet; Anne De Paepe
Journal:  Stroke Res Treat       Date:  2011-01-20

Review 10.  Fabry disease.

Authors:  Dominique P Germain
Journal:  Orphanet J Rare Dis       Date:  2010-11-22       Impact factor: 4.123

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  1 in total

1.  Apolipoprotein E polymorphisms are associated with ischemic stroke susceptibility in a Northwest China Han population.

Authors:  Li-Li Zhao; Gang Su; Li-Xia Chen; Qi Yan; Xue-Ping Wang; Wei Yuan; Lei Wang; Zhen-Chang Zhang
Journal:  Biosci Rep       Date:  2017-11-29       Impact factor: 3.840

  1 in total

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