| Literature DB >> 23333833 |
Maged Zeineldin1, Kristi L Neufeld.
Abstract
Mutation of tumor suppressor gene adenomatous polyposis coli (APC) is an initiating step in most colon cancers. This review summarizes Apc models in mice and rats, with particular concentration on those most recently developed, phenotypic variation among different models, and genotype/phenotype correlations.Entities:
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Year: 2013 PMID: 23333833 PMCID: PMC3655098 DOI: 10.1016/j.bbcan.2013.01.001
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002