Literature DB >> 23329767

Priapism in teenage boys following depot testosterone.

James F Donaldson1, Nikki Davis, Justin H Davies, Roland W Rees, Henrik A Steinbrecher.   

Abstract

Priapism is rare in children and may result in erectile dysfunction and sexual aversion behaviours. Testosterone therapy is commonly regarded as safe in children and is widely used in constitutional delay of growth and puberty, hypogonadism, hypospadias and micropenis. We report two cases of priapism in teenage boys with constitutional delay of growth and puberty after a change in the formulation of depot testosterone. One case required surgical intervention and the other was preceded by stuttering priapism. These cases illustrate the importance of patient and/or parent counselling before testosterone administration and consideration of lower doses in at-risk patients.

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Year:  2012        PMID: 23329767     DOI: 10.1515/jpem-2012-0270

Source DB:  PubMed          Journal:  J Pediatr Endocrinol Metab        ISSN: 0334-018X            Impact factor:   1.634


  4 in total

Review 1.  Molecular pathophysiology of priapism: emerging targets.

Authors:  Uzoma A Anele; Belinda F Morrison; Arthur L Burnett
Journal:  Curr Drug Targets       Date:  2015       Impact factor: 3.465

2.  Nitrergic Mechanisms for Management of Recurrent Priapism.

Authors:  Uzoma A Anele; Arthur L Burnett
Journal:  Sex Med Rev       Date:  2015-06-04

3.  Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis.

Authors:  B Musicki; S Karakus; W Akakpo; F H Silva; J Liu; H Chen; B R Zirkin; A L Burnett
Journal:  Andrology       Date:  2017-11-16       Impact factor: 3.842

Review 4.  Testosterone Deficiency in Sickle Cell Disease: Recognition and Remediation.

Authors:  Biljana Musicki; Arthur L Burnett
Journal:  Front Endocrinol (Lausanne)       Date:  2022-05-03       Impact factor: 6.055

  4 in total

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