PURPOSE: Cancer is the second leading cause of death in the United States and mortality varies by ethnicity. The objective of this study was to examine the association between cancer mortality and dietary intake among a large multiethnic population. METHODS: A prospective cohort design was used to examine cancer mortality among 146,389 participants. Multiethnic cohort study participants represent five ethnic groups: African American, Native Hawaiian, Japanese American, Latino, and Caucasian. Hazard ratios for cancer mortality by intake levels of five food groups and discretionary fat were calculated using Cox proportional hazards models stratified by sex and ethnicity. RESULTS: There were a total of 2,028 male and 1,464 female fatal cancer cases at the end of follow-up. Among Japanese American men only, there was a significant protective effect seen in those reporting a high grain intake (HR = 0.49, 95 % CI 0.35-0.69); there was no effect of grain consumption in any other ethnic-sex group. There was no evidence that ethnicity modified associations between fruit, vegetable, meat, dairy, or discretionary fat intake and cancer mortality among men. Associations between food group consumption and risk for cancer mortality among women were similar across ethnic groups. CONCLUSIONS: The considerable reduction in cancer risk associated with high grain consumption among a specific ethnic-sex group, Japanese American men, warrants further investigation. Additional research is needed to validate this observation and determine whether this was a chance finding, or possibly due to differential intake of specific grain subtypes, and/or related to a sex-specific cancer type.
PURPOSE:Cancer is the second leading cause of death in the United States and mortality varies by ethnicity. The objective of this study was to examine the association between cancer mortality and dietary intake among a large multiethnic population. METHODS: A prospective cohort design was used to examine cancer mortality among 146,389 participants. Multiethnic cohort study participants represent five ethnic groups: African American, Native Hawaiian, Japanese American, Latino, and Caucasian. Hazard ratios for cancer mortality by intake levels of five food groups and discretionary fat were calculated using Cox proportional hazards models stratified by sex and ethnicity. RESULTS: There were a total of 2,028 male and 1,464 female fatal cancer cases at the end of follow-up. Among Japanese American men only, there was a significant protective effect seen in those reporting a high grain intake (HR = 0.49, 95 % CI 0.35-0.69); there was no effect of grain consumption in any other ethnic-sex group. There was no evidence that ethnicity modified associations between fruit, vegetable, meat, dairy, or discretionary fat intake and cancer mortality among men. Associations between food group consumption and risk for cancer mortality among women were similar across ethnic groups. CONCLUSIONS: The considerable reduction in cancer risk associated with high grain consumption among a specific ethnic-sex group, Japanese American men, warrants further investigation. Additional research is needed to validate this observation and determine whether this was a chance finding, or possibly due to differential intake of specific grain subtypes, and/or related to a sex-specific cancer type.
Authors: D O Stram; J H Hankin; L R Wilkens; M C Pike; K R Monroe; S Park; B E Henderson; A M Nomura; M E Earle; F S Nagamine; L N Kolonel Journal: Am J Epidemiol Date: 2000-02-15 Impact factor: 4.897
Authors: Brian N Fink; Mia M Gaudet; Julie A Britton; Page E Abrahamson; Susan L Teitelbaum; Judith Jacobson; Paula Bell; Joyce A Thomas; Geoffrey C Kabat; Alfred I Neugut; Marilie D Gammon Journal: Breast Cancer Res Treat Date: 2006-03-15 Impact factor: 4.872
Authors: Timothy J Key; Arthur Schatzkin; Walter C Willett; Naomi E Allen; Elizabeth A Spencer; Ruth C Travis Journal: Public Health Nutr Date: 2004-02 Impact factor: 4.022
Authors: Amanda J Cross; Michael F Leitzmann; Mitchell H Gail; Albert R Hollenbeck; Arthur Schatzkin; Rashmi Sinha Journal: PLoS Med Date: 2007-12 Impact factor: 11.069
Authors: Shenghui Wu; Susan P Fisher-Hoch; Belinda M Reininger; Miryoung Lee; Joseph B McCormick Journal: Nutr Cancer Date: 2019-04-24 Impact factor: 2.900
Authors: Bonnie E Gould Rothberg; Kaleigh J Bulloch; Judith A Fine; Raymond L Barnhill; Marianne Berwick Journal: Cancer Epidemiol Date: 2014-09-05 Impact factor: 2.984
Authors: Dagfinn Aune; NaNa Keum; Edward Giovannucci; Lars T Fadnes; Paolo Boffetta; Darren C Greenwood; Serena Tonstad; Lars J Vatten; Elio Riboli; Teresa Norat Journal: BMJ Date: 2016-06-14
Authors: Dagfinn Aune; Edward Giovannucci; Paolo Boffetta; Lars T Fadnes; NaNa Keum; Teresa Norat; Darren C Greenwood; Elio Riboli; Lars J Vatten; Serena Tonstad Journal: Int J Epidemiol Date: 2017-06-01 Impact factor: 7.196
Authors: Tina Sehm; Zheng Fan; Ruth Weiss; Marc Schwarz; Tobias Engelhorn; Nirjhar Hore; Arnd Doerfler; Michael Buchfelder; Iiker Y Eyüpoglu; Nic E Savaskan Journal: Cancer Med Date: 2014-06-04 Impact factor: 4.452