Literature DB >> 23328479

Sphingosine 1-phosphate is a missing link between chronic inflammation and colon cancer.

Nigel J Pyne1, Susan Pyne.   

Abstract

In this issue of Cancer Cell, Liang and colleagues demonstrated that sphingosine kinase 1, the enzyme that catalyzes formation of the biologically active lipid sphingosine 1-phosphate, drives a malicious amplification loop involving sphingosine 1-phosphate receptor 1 and the NF-κB/IL-6/STAT3 pathway. This appears critical for progression from chronic inflammation to colon cancer.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Year:  2013        PMID： 23328479     DOI： 10.1016/j.ccr.2012.12.005

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  14 in total

1.  Vascular modulation through exercise improves chemotherapy efficacy in Ewing sarcoma.

Authors:  Miriam B G Morrell; Claudia Alvarez-Florez; Aiqian Zhang; Eugenie S Kleinerman; Hannah Savage; Enrica Marmonti; Minjeong Park; Angela Shaw; Keri L Schadler
Journal:  Pediatr Blood Cancer       Date:  2019-05-28       Impact factor: 3.167

Review 2.  An update on the biology of sphingosine 1-phosphate receptors.

Authors:  Victoria A Blaho; Timothy Hla
Journal:  J Lipid Res       Date:  2014-01-23       Impact factor: 5.922

3.  Crystal Structure of Sphingosine Kinase 1 with PF-543.

Authors:  Jing Wang; Stefan Knapp; Nigel J Pyne; Susan Pyne; Jonathan M Elkins
Journal:  ACS Med Chem Lett       Date:  2014-10-27       Impact factor: 4.345

4.  Hemorrhage-Induced Sphingosine Kinase 1 Contributes to Ferroptosis-Mediated Secondary Brain Injury in Intracerebral Hemorrhage.

Authors:  Xiaojun Diao; Qi Cui; Ning Tian; Zixian Zhou; Wenjing Xiang; Yanlin Jiang; Jungang Deng; Hongzhan Liao; Xiaohui Lin; Qinghua Li; Rujia Liao
Journal:  Mol Neurobiol       Date:  2022-01-07       Impact factor: 5.590

Review 5.  Cancer and inflammation.

Authors:  Lance L Munn
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2016-12-12

6.  Sphingolipids are required for efficient triacylglycerol loss in conjugated linoleic Acid treated adipocytes.

Authors:  Wei Wang; Michael Fromm
Journal:  PLoS One       Date:  2015-04-23       Impact factor: 3.240

Review 7.  Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.

Authors:  Diana Hatoum; Nahal Haddadi; Yiguang Lin; Najah T Nassif; Eileen M McGowan
Journal:  Oncotarget       Date:  2017-05-30

8.  Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.

Authors:  C Rutherford; S Childs; J Ohotski; L McGlynn; M Riddick; S MacFarlane; D Tasker; S Pyne; N J Pyne; J Edwards; T M Palmer
Journal:  Cell Death Dis       Date:  2013-11-21       Impact factor: 8.469

Review 9.  "Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer.

Authors:  Nahal Haddadi; Yiguang Lin; Ann M Simpson; Najah T Nassif; Eileen M McGowan
Journal:  Int J Mol Sci       Date:  2017-09-02       Impact factor: 5.923

10.  Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1.

Authors:  Ling-Wei Hii; Felicia Fei-Lei Chung; Chun Wai Mai; Zong Yang Yee; Hong Hao Chan; Vijay Joseph Raja; Noah Elias Dephoure; Nigel J Pyne; Susan Pyne; Chee-Onn Leong
Journal:  Cells       Date:  2020-04-04       Impact factor: 6.600
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