| Literature DB >> 23327832 |
Da-Song Yang1, You-Li Zhang, Wei-Bing Peng, Li-Yan Wang, Zi-Lei Li, Xue Wang, Ke-Chun Liu, Yong-Ping Yang, Hong-Lin Li, Xiao-Li Li.
Abstract
Four new jatropholane-type diterpenes (1-4), named sikkimenoids A-D, were isolated from the aerial parts of Euphorbia sikkimensis. The structural elucidations of 1-4 were accomplished by extensive NMR analyses, and their absolute configurations were established by ECD calculations. Compound 2 exhibited weak antiangiogenic activity with an IC(50) value of 43.0 μM when evaluated using a zebrafish model.Entities:
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Year: 2013 PMID： 23327832 DOI： 10.1021/np300799n
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050