Literature DB >> 23327571

Systems pharmacology meets predictive, preventive, personalized and participatory medicine.

Sherry L Jenkins, Avi Ma'ayan.   

Abstract

Entities:  

Mesh：

Year:  2013        PMID： 23327571      PMCID： PMC3605723          DOI： 10.2217/pgs.12.186

Source DB:  PubMed          Journal:  Pharmacogenomics        ISSN： 1462-2416            Impact factor:   2.533


× No keyword cloud information.
  13 in total

1.  Predicting adverse drug events using pharmacological network models.

Authors:  Aurel Cami; Alana Arnold; Shannon Manzi; Ben Reis
Journal:  Sci Transl Med       Date:  2011-12-21       Impact factor: 17.956

2.  Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers.

Authors:  Edward Y Chen; Huilei Xu; Simon Gordonov; Maribel P Lim; Matthew H Perkins; Avi Ma'ayan
Journal:  Bioinformatics       Date:  2011-11-10       Impact factor: 6.937

3.  Systems pharmacology of arrhythmias.

Authors:  Seth I Berger; Avi Ma'ayan; Ravi Iyengar
Journal:  Sci Signal       Date:  2010-04-20       Impact factor: 8.192

4.  The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Authors:  Justin Lamb; Emily D Crawford; David Peck; Joshua W Modell; Irene C Blat; Matthew J Wrobel; Jim Lerner; Jean-Philippe Brunet; Aravind Subramanian; Kenneth N Ross; Michael Reich; Haley Hieronymus; Guo Wei; Scott A Armstrong; Stephen J Haggarty; Paul A Clemons; Ru Wei; Steven A Carr; Eric S Lander; Todd R Golub
Journal:  Science       Date:  2006-09-29       Impact factor: 47.728

5.  The human microbiome project.

Authors:  Peter J Turnbaugh; Ruth E Ley; Micah Hamady; Claire M Fraser-Liggett; Rob Knight; Jeffrey I Gordon
Journal:  Nature       Date:  2007-10-18       Impact factor: 49.962

6.  Colliding dynamical complex network models: biological attractors versus attractors from material physics.

Authors:  Avi Ma'ayan
Journal:  Biophys J       Date:  2012-11-07       Impact factor: 4.033

7.  Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

Authors:  N P Tatonetti; J C Denny; S N Murphy; G H Fernald; G Krishnan; V Castro; P Yue; P S Tsao; P S Tsau; I Kohane; D M Roden; R B Altman
Journal:  Clin Pharmacol Ther       Date:  2011-05-25       Impact factor: 6.875

8.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

9.  A map of human genome variation from population-scale sequencing.

Authors:  Gonçalo R Abecasis; David Altshuler; Adam Auton; Lisa D Brooks; Richard M Durbin; Richard A Gibbs; Matt E Hurles; Gil A McVean
Journal:  Nature       Date:  2010-10-28       Impact factor: 49.962

10.  KEGG for representation and analysis of molecular networks involving diseases and drugs.

Authors:  Minoru Kanehisa; Susumu Goto; Miho Furumichi; Mao Tanabe; Mika Hirakawa
Journal:  Nucleic Acids Res       Date:  2009-10-30       Impact factor: 16.971
View more
  11 in total

1.  A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.

Authors:  Andrew M Stern; Mark E Schurdak; Ivet Bahar; Jeremy M Berg; D Lansing Taylor
Journal:  J Biomol Screen       Date:  2016-03-08

Review 2.  An integrated quantitative proteomics and systems biology approach to explore synaptic protein profile changes during morphine exposure.

Authors:  Steven D Stockton; Lakshmi A Devi
Journal:  Neuropsychopharmacology       Date:  2013-09-18       Impact factor: 7.853

3.  Lean Big Data integration in systems biology and systems pharmacology.

Authors:  Avi Ma'ayan; Andrew D Rouillard; Neil R Clark; Zichen Wang; Qiaonan Duan; Yan Kou
Journal:  Trends Pharmacol Sci       Date:  2014-08-07       Impact factor: 14.819

4.  Metasignatures identify two major subtypes of breast cancer.

Authors:  Q Duan; Y Kou; N R Clark; S Gordonov; A Ma'ayan
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2013-03-27

Review 5.  Implementation of quantitative and systems pharmacology in large pharma.

Authors:  S A G Visser; D P de Alwis; T Kerbusch; J A Stone; S R B Allerheiligen
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2014-10-22

6.  LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.

Authors:  Qiaonan Duan; Corey Flynn; Mario Niepel; Marc Hafner; Jeremy L Muhlich; Nicolas F Fernandez; Andrew D Rouillard; Christopher M Tan; Edward Y Chen; Todd R Golub; Peter K Sorger; Aravind Subramanian; Avi Ma'ayan
Journal:  Nucleic Acids Res       Date:  2014-06-06       Impact factor: 16.971

Review 7.  How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion.

Authors:  Douglas B Kell; Stephen G Oliver
Journal:  Front Pharmacol       Date:  2014-10-31       Impact factor: 5.810

8.  Individually tailored screening of susceptibility to sarcopenia using p53 codon 72 polymorphism, phenotypes, and conventional risk factors.

Authors:  Laura Di Renzo; Santo Gratteri; Francesca Sarlo; Andrea Cabibbo; Carmen Colica; Antonino De Lorenzo
Journal:  Dis Markers       Date:  2014-10-13       Impact factor: 3.434

9.  How to Screen and Prevent Metabolic Syndrome in Patients of PCOS Early: Implications From Metabolomics.

Authors:  Xiaoxuan Zhao; Xiaoling Feng; Xinjie Zhao; Yuepeng Jiang; Xianna Li; Jingyun Niu; Xiaoyu Meng; Jing Wu; Guowang Xu; Lihui Hou; Ying Wang
Journal:  Front Endocrinol (Lausanne)       Date:  2021-06-02       Impact factor: 5.555

10.  Personalized medicine: myth or reality? The position of Russian clinical pharmacologists.

Authors:  Anna S Zhestovskaja; Vladimir G Kukes; Dmitry A Sychev
Journal:  EPMA J       Date:  2013-05-11       Impact factor: 6.543
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.