Literature DB >> 23326118

Role of autoimmunity in primary biliary cirrhosis.

Tian-Yan Shi1, Feng-Chun Zhang.   

Abstract

Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by the presence of serum autoantibodies and chronic nonsuppurative destructive cholangitis. The pathogenesis of PBC involves environmental factors, genetic predisposition and loss of immune tolerance. In recent years, it has become univocally accepted that an inappropriately activated immune response is one of the most important factors in PBC. In this study, the role of autoimmunity in PBC is summarized and a feasible research orientation is recommended.

Entities:  

Keywords:  Autoimmunity; Cellular immunity; Humoral immunity; Nonspecific immunity; Primary biliary cirrhosis

Mesh：

Substances：

Year:  2012        PMID： 23326118      PMCID： PMC3544015          DOI： 10.3748/wjg.v18.i48.7141

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  87 in total

1.  Biochemical and immunologic effects of rituximab in patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid.

Authors:  Masanobu Tsuda; Yuki Moritoki; Zhe-Xiong Lian; Weici Zhang; Katsunori Yoshida; Kanji Wakabayashi; Guo-Xiang Yang; Toshio Nakatani; John Vierling; Keith Lindor; M Eric Gershwin; Christopher L Bowlus
Journal:  Hepatology       Date:  2012-02       Impact factor: 17.425

2.  Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis.

Authors:  Yutaka Honda; Satoshi Yamagiwa; Yasunobu Matsuda; Masaaki Takamura; Takafumi Ichida; Yutaka Aoyagi
Journal:  J Hepatol       Date:  2007-04-03       Impact factor: 25.083

3.  [The characteristics of peripheral lymphocytic subsets and cytokines in primary biliary and their changes to drug treatment.].

Authors:  Min Tang; Xu-Hua Shi; Feng-Chun Zhang
Journal:  Zhonghua Nei Ke Za Zhi       Date:  2010-02

4.  Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts.

Authors:  Kumiko Isse; Kenichi Harada; Yoh Zen; Takashi Kamihira; Shinji Shimoda; Mine Harada; Yasuni Nakanuma
Journal:  Hepatology       Date:  2005-03       Impact factor: 17.425

5.  The long-term effect of ursodeoxycholic acid on laboratory liver parameters in biochemically non-advanced primary biliary cirrhosis.

Authors:  E M M Kuiper; B E Hansen; W Lesterhuis; R J Robijn; J C Thijs; L G J B Engels; G H Koek; M N Aparicio; M J Kerbert-Dreteler; H R van Buuren
Journal:  Clin Res Hepatol Gastroenterol       Date:  2011-01       Impact factor: 2.947

6.  Diagnostic and clinical utility of antibodies against the nuclear body promyelocytic leukaemia and Sp100 antigens in patients with primary biliary cirrhosis.

Authors:  Maria G Mytilinaiou; Wolfgang Meyer; Thomas Scheper; Eirini I Rigopoulou; Christian Probst; Andreas L Koutsoumpas; Daniel Abeles; Andrew K Burroughs; Lars Komorowski; Diego Vergani; Dimitrios P Bogdanos
Journal:  Clin Chim Acta       Date:  2012-04-03       Impact factor: 3.786

7.  Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice.

Authors:  Sabine Oertelt; Zhe-Xiong Lian; Chun-Mei Cheng; Ya-Hui Chuang; Kerstien A Padgett; Xiao-Song He; William M Ridgway; Aftab A Ansari; Ross L Coppel; Ming O Li; Richard A Flavell; Mitchell Kronenberg; Ian R Mackay; M Eric Gershwin
Journal:  J Immunol       Date:  2006-08-01       Impact factor: 5.422

Review 8.  Antimitochondrial antibody-negative primary biliary cirrhosis.

Authors:  Gideon M Hirschfield; E J Heathcote
Journal:  Clin Liver Dis       Date:  2008-05       Impact factor: 6.126

9.  Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis.

Authors:  January T Salas; Jesús M Banales; Sarai Sarvide; Sergio Recalde; Alex Ferrer; Iker Uriarte; Ronald P J Oude Elferink; Jesús Prieto; Juan F Medina
Journal:  Gastroenterology       Date:  2008-02-14       Impact factor: 22.682

10.  Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice.

Authors:  Willy Hsu; Weici Zhang; Koichi Tsuneyama; Yuki Moritoki; William M Ridgway; Aftab A Ansari; Ross L Coppel; Zhe-Xiong Lian; Ian Mackay; M Eric Gershwin
Journal:  Hepatology       Date:  2009-01       Impact factor: 17.425
View more
  5 in total

Review 1.  Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis.

Authors:  Vasiliy Ivanovich Reshetnyak
Journal:  World J Gastroenterol       Date:  2015-07-07       Impact factor: 5.742

2.  Clinicopathological study of primary biliary cirrhosis with interface hepatitis compared to autoimmune hepatitis.

Authors:  Mio Kobayashi; Yuko Kakuda; Kenichi Harada; Yasunori Sato; Motoko Sasaki; Hiroko Ikeda; Mitsuhiro Terada; Munenori Mukai; Shuichi Kaneko; Yasuni Nakanuma
Journal:  World J Gastroenterol       Date:  2014-04-07       Impact factor: 5.742

Review 3.  Eosinophils in Autoimmune Diseases.

Authors:  Nicola L Diny; Noel R Rose; Daniela Čiháková
Journal:  Front Immunol       Date:  2017-04-27       Impact factor: 7.561

Review 4.  NK Cell Subtypes as Regulators of Autoimmune Liver Disease.

Authors:  Guohui Jiao; Bangmao Wang
Journal:  Gastroenterol Res Pract       Date:  2016-07-04       Impact factor: 2.260

5.  The Distribution and the Fibrotic Role of Elevated Inflammatory Th17 Cells in Patients With Primary Biliary Cirrhosis.

Authors:  TianYan Shi; Ting Zhang; LiNa Zhang; YunJiao Yang; HaoZe Zhang; FengChun Zhang
Journal:  Medicine (Baltimore)       Date:  2015-11       Impact factor: 1.889
  5 in total

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