Literature DB >> 23324067

Total synthesis of paracaseolide A.

Tezcan Guney1, George A Kraus.   

Abstract

The total synthesis of paracaseolide A, a valuable cell-cycle progression inhibitor, was accomplished in 8 steps from known compounds, with 6.6% overall yield. The synthetic strategy creates strong potential for diversification.

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Year:  2013        PMID: 23324067     DOI: 10.1021/ol303447r

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Catalytic Hydroxycyclopropanol Ring-Opening Carbonylative Lactonization to Fused Bicyclic Lactones.

Authors:  Xinpei Cai; Weida Liang; Mingxin Liu; Xiating Li; Mingji Dai
Journal:  J Am Chem Soc       Date:  2020-07-27       Impact factor: 15.419

2.  Diels-Alderase-free, bis-pericyclic, [4+2] dimerization in the biosynthesis of (±)-paracaseolide A.

Authors:  Tao Wang; Thomas R Hoye
Journal:  Nat Chem       Date:  2015-06-22       Impact factor: 24.427

Review 3.  Synthesis and Structural Modification of Marine Natural Products.

Authors:  Juan Zhang; Hua Zhang; Luis Alexandre Muehlmann; Cheng-Shi Jiang; Yue-Wei Guo
Journal:  Molecules       Date:  2017-05-26       Impact factor: 4.411

  3 in total

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