Literature DB >> 2332392

Bromocriptine-induced reduction of body fat in pigs.

L L Southern1, A H Cincotta, A H Meier, T D Bidner, K L Watkins.   

Abstract

An experiment was conducted with 36 crossbred finishing pigs (18 male castrates and 18 females) to evaluate the effect of bromocriptine implants on growth, feed intake, feed efficiency, plasma urea nitrogen (PUN) and carcass characteristics. Three levels of bromocriptine (0, 5 and 10 mg/[pig.d]) were administered, via implants at the base of the ear, to six (two replicates of three) male castrates or to six (two replicates of three) intact female pigs (2 x 3 factorial arrangement of treatments). Average initial weight of pigs at the time of implantation was 89.7 kg, and the implants remained in the pigs for 28 (replicate 1) or 30 (replicate 2) d prior to slaughter. Gain, feed intake and efficiency of feed utilization were not affected (P greater than .10) by bromocriptine. Plasma urea nitrogen was lower in female pigs administered 10 mg bromocriptine; bromocriptine did not affect PUN of male pigs (gender x bromocriptine, P less than .08). Tenth rib fat thickness and average backfat thickness were lower (P less than .06) and percentage of muscling was higher (P less than .06) in pigs implanted with bromocriptine. Female pigs had less 10th rib fat but larger loin eye areas and a greater percentage of muscling than male pigs.

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Year:  1990        PMID: 2332392     DOI: 10.2527/1990.684931x

Source DB:  PubMed          Journal:  J Anim Sci        ISSN: 0021-8812            Impact factor:   3.159


  6 in total

1.  Timed bromocriptine administration reduces body fat stores in obese subjects and hyperglycemia in type II diabetics.

Authors:  A H Meier; A H Cincotta; W C Lovell
Journal:  Experientia       Date:  1992-03-15

2.  Bromocriptine mesylate: Food and Drug Administration approved new approach in therapy of non-insulin dependant diabetes mellitus with poor glycemic control.

Authors:  Yogendra Keche
Journal:  J Pharm Bioallied Sci       Date:  2010-04

3.  Bromocriptine in type 2 diabetes mellitus.

Authors:  C Shivaprasad; Sanjay Kalra
Journal:  Indian J Endocrinol Metab       Date:  2011-07

4.  Bromocriptine approved as the first medication to target dopamine activity to improve glycemic control in patients with type 2 diabetes.

Authors:  Michael A Via; Himani Chandra; Takako Araki; Matthew V Potenza; Maria Skamagas
Journal:  Diabetes Metab Syndr Obes       Date:  2010-03-26       Impact factor: 3.168

5.  A randomized, double-blind, placebo-controlled trial to assess safety and tolerability during treatment of type 2 diabetes with usual diabetes therapy and either Cycloset or placebo.

Authors:  Richard E Scranton; J Michael Gaziano; Dean Rutty; Michael Ezrokhi; Anthony Cincotta
Journal:  BMC Endocr Disord       Date:  2007-06-25       Impact factor: 2.763

6.  Bromocriptine and insulin sensitivity in lean and obese subjects.

Authors:  L Bahler; H J Verberne; E Brakema; R Tepaske; J Booij; J B Hoekstra; F Holleman
Journal:  Endocr Connect       Date:  2016-10-10       Impact factor: 3.335

  6 in total

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