| Literature DB >> 23321013 |
Hudson Caetano Polonini1, Larissa Lavorato Lima, Karla Mara Gonçalves, Antônio Márcio Resende do Carmo, Adilson David da Silva, Nádia Rezende Barbosa Raposo.
Abstract
Resveratrol is a promising agent for protecting human skin from UV radiation and to reduce the occurrence of cutaneous malignancies. We describe the photoprotective activity of six resveratrol analogues using the diffuse transmittance technique to determine the SPF and the protection against UVA radiation. The analogues presented a varied profile of photoprotection, the SPF ranging from 2 to 10 and the UVAPF from 0 to 9. Among the six compounds tested, the protection against UVB sunrays provided by compound B was more significant than the protection provided by resveratrol; compounds C, D, E and F show photoprotection similar to resveratrol.Entities:
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Year: 2012 PMID： 23321013 DOI： 10.1016/j.bmc.2012.11.052
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641