Literature DB >> 23320752

Collagen stimulating effect of peptide amphiphile C16-KTTKS on human fibroblasts.

Roanne R Jones1, Valeria Castelletto, Che J Connon, Ian W Hamley.   

Abstract

The collagen production of human dermal and corneal fibroblasts in contact with solutions of the peptide amphiphile (PA) C16-KTTKS is investigated and related to its self-assembly into nanotape structures. This PA is used in antiwrinkle cosmeceutical applications (trade name Matrixyl). We prove that C16-KTTKS stimulates collagen production in a concentration-dependent manner close to the critical aggregation concentration determined from pyrene fluorescence spectroscopy. This suggests that self-assembly and the stimulation of collagen production are inter-related.

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Year:  2013        PMID： 23320752     DOI： 10.1021/mp300549d

Source DB:  PubMed          Journal:  Mol Pharm        ISSN： 1543-8384            Impact factor:   4.939


  12 in total

Review 1.  Self-Assembled Peptide Nanostructures for ECM Biomimicry.

Authors:  Davide Marin; Silvia Marchesan
Journal:  Nanomaterials (Basel)       Date:  2022-06-22       Impact factor: 5.719

2.  New self-assembling multifunctional templates for the biofabrication and controlled self-release of cultured tissue.

Authors:  Ricardo M Gouveia; Valeria Castelletto; Ian W Hamley; Che J Connon
Journal:  Tissue Eng Part A       Date:  2015-03-24       Impact factor: 3.845

3.  Supra-molecular assembly of a lumican-derived peptide amphiphile enhances its collagen-stimulating activity.

Authors:  Merlin N M Walter; Ashkan Dehsorkhi; Ian W Hamley; Che J Connon
Journal:  Biomater Sci       Date:  2016-02       Impact factor: 6.843

Review 4.  Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature.

Authors:  Caroline Aldag; Diana Nogueira Teixeira; Phillip S Leventhal
Journal:  Clin Cosmet Investig Dermatol       Date:  2016-11-09

Review 5.  Peptide hormones and lipopeptides: from self-assembly to therapeutic applications.

Authors:  J A Hutchinson; S Burholt; I W Hamley
Journal:  J Pept Sci       Date:  2017-01-27       Impact factor: 1.905

6.  Turning a Collagenesis-Inducing Peptide Into a Potent Antibacterial and Antibiofilm Agent Against Multidrug-Resistant Gram-Negative Bacteria.

Authors:  Ana Gomes; Lucinda J Bessa; Iva Fernandes; Ricardo Ferraz; Nuno Mateus; Paula Gameiro; Cátia Teixeira; Paula Gomes
Journal:  Front Microbiol       Date:  2019-08-20       Impact factor: 5.640

7.  The Effects of a Novel Series of KTTKS Analogues on Cytotoxicity and Proteolytic Activity.

Authors:  Urszula Tałałaj; Paulina Uścinowicz; Irena Bruzgo; Arkadiusz Surażyński; Ilona Zaręba; Agnieszka Markowska
Journal:  Molecules       Date:  2019-10-15       Impact factor: 4.411

8.  Self-Assembly, Tunable Hydrogel Properties, and Selective Anti-Cancer Activity of a Carnosine-Derived Lipidated Peptide.

Authors:  Valeria Castelletto; Charlotte J C Edwards-Gayle; Francesca Greco; Ian W Hamley; Jani Seitsonen; Janne Ruokolainen
Journal:  ACS Appl Mater Interfaces       Date:  2019-09-03       Impact factor: 9.229

Review 9.  Peptide Amphiphiles in Corneal Tissue Engineering.

Authors:  Martina Miotto; Ricardo M Gouveia; Che J Connon
Journal:  J Funct Biomater       Date:  2015-08-06

Review 10.  Self-assembling amphiphilic peptides.

Authors:  Ashkan Dehsorkhi; Valeria Castelletto; Ian W Hamley
Journal:  J Pept Sci       Date:  2014-04-13       Impact factor: 1.905
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