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Literature DB >> 23318795

The novel CTX-M-116 β-lactamase gene discovered in Proteus mirabilis is composed of parts of the CTX-M-22 and CTX-M-23 genes.

N Fursova¹, S Pryamchuk, A Kruglov, I Abaev, E Pecherskikh, N Kartsev, E Svetoch, I Dyatlov.

Abstract

The novel β-lactamase gene bla(CTX-M-116) was identified in a Proteus mirabilis nosocomial isolate recovered from the urine of a patient in Moscow in 2005. DNA sequence analysis showed bla(CTX-M-116) to be a hybrid gene consisting of 5' bla(CTX-M-23) (nucleotides 1 to 278) and 3' bla(CTX-M-22) (nucleotides 286 to 876) moieties separated by an intervening putative site of recombination (GTTAAAT). A retrospective analysis of available bla(CTX-M) genes in the GenBank database revealed 19 bla(CTX-M) genes that display the same hybrid structure.

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Year: 2013 PMID： 23318795 PMCID： PMC3591887 DOI： 10.1128/AAC.01471-12

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

25 in total

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2. [An algorithm for identification of CTX-M-type beta-lactamase genes using restriction fragment length polymorphism analysis of PCR-product].

Authors: S D Priamchuk; N K Fursova; V A Anisimova; Iu N Kovalev; I V Abaev; E N Kuzhel'naia; E A Svetoch
Journal: Mol Gen Mikrobiol Virusol Date: 2011

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Authors: Gang Liu; Bao-Dong Ling; Yong-En Xie; Li Lin; Yun Zeng; Xiang Zhang; Jun Lei
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Review 4. Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.

Authors: Karen Bush; Jed F Fisher
Journal: Annu Rev Microbiol Date: 2011 Impact factor: 15.500

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Authors: N K Fursova; S D Pryamchuk; I V Abaev; Yu N Kovalev; N A Shishkova; E I Pecherskikh; O V Korobova; E I Astashkin; D M Pachkunov; E A Svetoch; S V Sidorenko
Journal: Antibiot Khimioter Date: 2010

Review 6. Analysis of antibiotic resistance regions in Gram-negative bacteria.

Authors: Sally R Partridge
Journal: FEMS Microbiol Rev Date: 2011-06-16 Impact factor: 16.408

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Journal: Clin Microbiol Infect Date: 2010-09 Impact factor: 8.067

8. [Genetic determinants of antibacterial resistance among nosocomial Escherichia coli, Klebsiella spp., and Enterobacter spp. isolates collected in Russia within 2003-2007].

Authors: S D Priamchuk; N K Fursova; I V Abaev; Iu N Kovalev; N A Shishkova; E I Pecherskikh; O V Korobova; E I Astashkin; D M Pachkunov; A N Kruglov; D V Ivanov; S V Sidorenko; E A Svetoch; I A Diatlov
Journal: Antibiot Khimioter Date: 2010

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