Literature DB >> 23318660

Measuring psychosocial outcome is good.

Ashleigh Lin1, Stephen J Wood, Alison R Yung.   

Abstract

PURPOSE OF REVIEW: Poor psychosocial functioning in schizophrenia can be conceptualized as an early indicator of chronic neurodevelopmental illness. Alternatively, impaired psychosocial functioning could be the result of social and environmental factors associated with the onset of psychotic illness. We review recent evidence on psychosocial outcome in the early phases of psychotic illness, when young people are less removed from their developmental trajectory, any brain changes may be mutable and there may be greater opportunity for intervention. RECENT
FINDINGS: In samples with first-episode psychosis, poor premorbid functioning, stable negative symptoms and impaired social cognition and neurocognition may indicate individuals likely to experience poor psychosocial outcome. There is also some evidence of social/environmental predictors of poor outcome. Recent findings from at-risk samples suggest similar patterns, although more research is needed.
SUMMARY: It is likely that for some patients poor psychosocial outcome is the result of longstanding neurological changes, whereas for others it is related to the secondary consequences of having psychosis. We suggest that measuring psychosocial outcome in the early stages of psychosis is important for our understanding of the cause of schizophrenia, but argue for the importance of the patient's subjective view on their psychosocial recovery.

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Year:  2013        PMID: 23318660     DOI: 10.1097/YCO.0b013e32835d82aa

Source DB:  PubMed          Journal:  Curr Opin Psychiatry        ISSN: 0951-7367            Impact factor:   4.741


  15 in total

1.  The relationship of attitudinal beliefs to negative symptoms, neurocognition, and daily functioning in recent-onset schizophrenia.

Authors:  Joseph Ventura; Kenneth L Subotnik; Arielle Ered; Denise Gretchen-Doorly; Gerhard S Hellemann; Anja Vaskinn; Keith H Nuechterlein
Journal:  Schizophr Bull       Date:  2014-02-21       Impact factor: 9.306

2.  Early life stress disrupts social behavior and prefrontal cortex parvalbumin interneurons at an earlier time-point in females than in males.

Authors:  Freedom H Holland; Prabarna Ganguly; David N Potter; Elena H Chartoff; Heather C Brenhouse
Journal:  Neurosci Lett       Date:  2014-02-22       Impact factor: 3.046

3.  Potentially important periods of change in the development of social and role functioning in youth at clinical high risk for psychosis.

Authors:  Eva Velthorst; Jamie Zinberg; Jean Addington; Kristin S Cadenhead; Tyrone D Cannon; Ricardo E Carrión; Andrea Auther; Barbara A Cornblatt; Thomas H McGlashan; Daniel H Mathalon; Diana O Perkins; Larry J Seidman; Ming T Tsuang; Elaine F Walker; Scott W Woods; Abraham Reichenberg; Carrie E Bearden
Journal:  Dev Psychopathol       Date:  2017-04-19

4.  Clozapine and Psychosocial Function in Schizophrenia: A Systematic Review and Meta-Analysis.

Authors:  Andrew T Olagunju; Scott R Clark; Bernhard T Baune
Journal:  CNS Drugs       Date:  2018-11       Impact factor: 5.749

5.  Neuroanatomical Predictors of Functional Outcome in Individuals at Ultra-High Risk for Psychosis.

Authors:  Renate L E P Reniers; Ashleigh Lin; Alison R Yung; Nikolaos Koutsouleris; Barnaby Nelson; Vanessa L Cropley; Dennis Velakoulis; Patrick D McGorry; Christos Pantelis; Stephen J Wood
Journal:  Schizophr Bull       Date:  2017-03-01       Impact factor: 9.306

6.  Validating a strategy for psychosocial phenotyping using a large corpus of clinical text.

Authors:  Adi V Gundlapalli; Andrew Redd; Marjorie Carter; Guy Divita; Shuying Shen; Miland Palmer; Matthew H Samore
Journal:  J Am Med Inform Assoc       Date:  2013-10-29       Impact factor: 4.497

7.  Vulnerability to psychosocial disability in psychosis.

Authors:  S L Griffiths; S J Wood; M Birchwood
Journal:  Epidemiol Psychiatr Sci       Date:  2018-09-12       Impact factor: 6.892

8.  Onset and transition of and recovery from adverse development: Study methodology.

Authors:  Johanna T W Wigman; Gerdina H M Pijnenborg; Richard Bruggeman; Maarten Vos; Anita Wessels; Inez Oosterholt; Maaike Nauta; Renee Stelwagen; Lana Otto; Anniek Wester; Lex Wunderink; Esther Sportel; Nynke Boonstra
Journal:  Early Interv Psychiatry       Date:  2019-11-05       Impact factor: 2.732

9.  Psychotic symptoms, functioning and coping in adolescents with mental illness.

Authors:  Johanna T W Wigman; Nina Devlin; Ian Kelleher; Aileen Murtagh; Michelle Harley; Anne Kehoe; Carol Fitzpatrick; Mary Cannon
Journal:  BMC Psychiatry       Date:  2014-04-01       Impact factor: 3.630

10.  Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects.

Authors:  Natalya P Bondar; Arina A Lepeshko; Vasiliy V Reshetnikov
Journal:  Behav Neurol       Date:  2018-01-09       Impact factor: 3.342

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