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Literature DB >> 23318295

Alzheimer disease: Arrestin' Alzheimer disease progression? β-arrestin 2 is a potential therapeutic target.

Heather Wood.

Abstract

Entities: Disease Gene

Year: 2013 PMID： 23318295 DOI： 10.1038/nrneurol.2012.278

Source DB: PubMed Journal: Nat Rev Neurol ISSN： 1759-4758 Impact factor: 42.937

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2 in total

1. The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

Authors: Amantha Thathiah; Kurt Spittaels; Marcel Hoffmann; Mik Staes; Adrian Cohen; Katrién Horré; Mieke Vanbrabant; Frea Coun; Veerle Baekelandt; André Delacourte; David F Fischer; Dirk Pollet; Bart De Strooper; Pascal Merchiers
Journal: Science Date: 2009-02-13 Impact factor: 47.728

2. β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Authors: Amantha Thathiah; Katrien Horré; An Snellinx; Elke Vandewyer; Yunhong Huang; Marta Ciesielska; Gerdien De Kloe; Sebastian Munck; Bart De Strooper
Journal: Nat Med Date: 2012-12-02 Impact factor: 53.440

2 in total

3 in total

Alzheimer disease: Arrestin' Alzheimer disease progression? β-arrestin 2 is a potential therapeutic target.

1. The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

2. β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Review 1. β-Arrestins as potential therapeutic targets for Alzheimer's disease.

2. Prediction of miRNA-mRNA associations in Alzheimer's disease mice using network topology.

3. COX-1/PGE₂/EP4 alleviates mucosal injury by upregulating β-arr1-mediated Akt signaling in colitis.

Alzheimer disease: Arrestin' Alzheimer disease progression? β-arrestin 2 is a potential therapeutic target.

1. The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

2. β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Review 1. β-Arrestins as potential therapeutic targets for Alzheimer's disease.

2. Prediction of miRNA-mRNA associations in Alzheimer's disease mice using network topology.

3. COX-1/PGE2/EP4 alleviates mucosal injury by upregulating β-arr1-mediated Akt signaling in colitis.

3. COX-1/PGE₂/EP4 alleviates mucosal injury by upregulating β-arr1-mediated Akt signaling in colitis.