Literature DB >> 23317914

Developing allelic and stutter peak height models for a continuous method of DNA interpretation.

Jo-Anne Bright1, Duncan Taylor, James M Curran, John S Buckleton.   

Abstract

Traditional forensic DNA interpretation methods are restricted as they are unable to deal completely with complex low level or mixed DNA profiles. This type of data has become more prevalent as DNA typing technologies become more sensitive. In addition they do not make full use of the information available in peak heights. Existing methods of interpretation are often described as binary which describes the fact that the probability of the evidence is assigned as 0 or 1 (hence binary) (see for example [1] at 7.3.3). These methods are being replaced by more advanced interpretation methods such as continuous models. In this paper we describe a series of models that can be used to calculate expected values for allele and stutter peak heights, and their ratio SR. This model could inform methods which implement a continuous method for the interpretation of DNA profiling data.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

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Year:  2013        PMID: 23317914     DOI: 10.1016/j.fsigen.2012.11.013

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  10 in total

1.  Towards developing forensically relevant single-cell pipelines by incorporating direct-to-PCR extraction: compatibility, signal quality, and allele detection.

Authors:  Nidhi Sheth; Harish Swaminathan; Amanda J Gonzalez; Ken R Duffy; Catherine M Grgicak
Journal:  Int J Legal Med       Date:  2021-01-23       Impact factor: 2.686

2.  Developmental validation of a 6-dye STR kit with 27 loci.

Authors:  Shuanglin Li; Ling Chen; Yanfang Wang; Quyi Xu; Hong Liu; Yue Li; Chao Liu
Journal:  Int J Legal Med       Date:  2017-04-12       Impact factor: 2.686

3.  Massively parallel sequencing-enabled mixture analysis of mitochondrial DNA samples.

Authors:  Jennifer D Churchill; Monika Stoljarova; Jonathan L King; Bruce Budowle
Journal:  Int J Legal Med       Date:  2018-02-22       Impact factor: 2.686

4.  MaSTR™: an effective probabilistic genotyping tool for interpretation of STR mixtures associated with differentially degraded DNA.

Authors:  Mitchell M Holland; Teresa M Tiedge; Abigail J Bender; Sidney A Gaston-Sanchez; Jennifer A McElhoe
Journal:  Int J Legal Med       Date:  2022-01-29       Impact factor: 2.686

5.  Flanking Variation Influences Rates of Stutter in Simple Repeats.

Authors:  August E Woerner; Jonathan L King; Bruce Budowle
Journal:  Genes (Basel)       Date:  2017-11-17       Impact factor: 4.096

Review 6.  A Review of Probabilistic Genotyping Systems: EuroForMix, DNAStatistX and STRmix™.

Authors:  Peter Gill; Corina Benschop; John Buckleton; Øyvind Bleka; Duncan Taylor
Journal:  Genes (Basel)       Date:  2021-09-30       Impact factor: 4.096

7.  Cell Subsampling Recovers Probative DNA Profile Information from Unresolvable/Undetectable Minor Donors in Mixtures.

Authors:  Kaitlin Huffman; Erin Hanson; Jack Ballantyne
Journal:  Genes (Basel)       Date:  2022-06-22       Impact factor: 4.141

8.  DNA capture and next-generation sequencing can recover whole mitochondrial genomes from highly degraded samples for human identification.

Authors:  Jennifer E L Templeton; Paul M Brotherton; Bastien Llamas; Julien Soubrier; Wolfgang Haak; Alan Cooper; Jeremy J Austin
Journal:  Investig Genet       Date:  2013-12-02

9.  Low temperature isothermal amplification of microsatellites drastically reduces stutter artifact formation and improves microsatellite instability detection in cancer.

Authors:  Antoine Daunay; Alex Duval; Laura G Baudrin; Olivier Buhard; Victor Renault; Jean-François Deleuze; Alexandre How-Kit
Journal:  Nucleic Acids Res       Date:  2019-12-02       Impact factor: 16.971

10.  Data on likelihood ratios of two-person DNA mixtures interpreted using semi- and fully continuous systems.

Authors:  Jae Joseph Russell B Rodriguez; Jo-Anne Bright; Jazelyn M Salvador; Rita P Laude; Maria Corazon A De Ungria
Journal:  Data Brief       Date:  2019-09-04
  10 in total

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