Literature DB >> 23316721

Propranolol treatment of infantile hemangiomas: anticipatory guidance for parents and caretakers.

Kari Martin1, Francine Blei, Francine Bleib, Sarah L Chamlin, Yvonne E Chiu, Ilona J Frieden, Peter C Frommelt, Maria C Garzon, Eun-Kyung M Kwon, Susan MacLellan-Tobert, Anthony J Mancini, Marcia Seefeldt, Robert Sidbury, Dawn H Siegel, Beth A Drolet, Robert J Boucek.   

Abstract

Infantile hemangiomas (IH) are benign tumors of endothelial-like cells. Occurring in 4.5% of children, they are the most common tumor of childhood. The great majority of patients with IH will not need treatment, but 10% require systemic treatment. Many treatments have been described for the treatment of IH, but the Food and Drug Administration has not approved any. Over the last decade, numerous reports of successful treatment of IH with propranolol have been published. Despite its widespread use, little is known regarding the proper dosing, safety monitoring, and during of treatment or long-term outcomes for propranolol treatment of IH. Given its potential side effects, detailed education regarding proper administration of the medication as well as warning signs to watch for is necessary for parents and caretakers. Herein, we provide a parental handout that practitioners can individually tailor for use in their clinics when educating parents and caretakers about the use of propranolol for IH. Updates will also need to be made as more is learned regarding the optimal dosing and safety monitoring when using propranolol for this indication.
© 2013 Wiley Periodicals, Inc.

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Year:  2013        PMID: 23316721      PMCID: PMC4786439          DOI: 10.1111/pde.12022

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN: 0736-8046            Impact factor:   1.588


  9 in total

1.  [Infantile hemangioma. Successful treatment with propranolol].

Authors:  J Baetz; S Eigelshoven; J Marquard; D Bruch-Gerharz; B Homey; T Meissner
Journal:  Hautarzt       Date:  2010-04       Impact factor: 0.751

2.  Hypoglycemia in children taking propranolol for the treatment of infantile hemangioma.

Authors:  Kristen E Holland; Ilona J Frieden; Peter C Frommelt; Anthony J Mancini; David Wyatt; Beth A Drolet
Journal:  Arch Dermatol       Date:  2010-07

3.  Propranolol for complicated infantile haemangiomas: a case series of 30 infants.

Authors:  F Manunza; S Syed; B Laguda; J Linward; H Kennedy; K Gholam; M Glover; A Giardini; J I Harper
Journal:  Br J Dermatol       Date:  2010-01-06       Impact factor: 9.302

4.  Propranolol for severe hemangiomas of infancy.

Authors:  Christine Léauté-Labrèze; Eric Dumas de la Roque; Thomas Hubiche; Franck Boralevi; Jean-Benoît Thambo; Alain Taïeb
Journal:  N Engl J Med       Date:  2008-06-12       Impact factor: 91.245

5.  Adverse effects of propranolol when used in the treatment of hemangiomas: a case series of 28 infants.

Authors:  Marlies de Graaf; Johannes M P J Breur; Martine F Raphaël; Marike Vos; Corstiaan C Breugem; Suzanne G M A Pasmans
Journal:  J Am Acad Dermatol       Date:  2011-05-20       Impact factor: 11.527

6.  Prospective study of infantile hemangiomas: clinical characteristics predicting complications and treatment.

Authors:  Anita N Haggstrom; Beth A Drolet; Eulalia Baselga; Sarah L Chamlin; Maria C Garzon; Kimberly A Horii; Anne W Lucky; Anthony J Mancini; Denise W Metry; Brandon Newell; Amy J Nopper; Ilona J Frieden
Journal:  Pediatrics       Date:  2006-09       Impact factor: 7.124

7.  Efficacy and safety of propranolol as first-line treatment for infantile hemangiomas.

Authors:  Clemens Schiestl; Kathrin Neuhaus; Silke Zoller; Ulrike Subotic; Ishilde Forster-Kuebler; Rike Michels; Christian Balmer; Lisa Weibel
Journal:  Eur J Pediatr       Date:  2010-10-09       Impact factor: 3.183

8.  Propranolol for severe infantile hemangiomas: follow-up report.

Authors:  Véronique Sans; Eric Dumas de la Roque; Jérôme Berge; Nicolas Grenier; Franck Boralevi; Juliette Mazereeuw-Hautier; Dan Lipsker; Elisabeth Dupuis; Khaled Ezzedine; Pierre Vergnes; Alain Taïeb; Christine Léauté-Labrèze
Journal:  Pediatrics       Date:  2009-08-10       Impact factor: 7.124

Review 9.  Initiation and use of propranolol for infantile hemangioma: report of a consensus conference.

Authors:  Beth A Drolet; Peter C Frommelt; Sarah L Chamlin; Anita Haggstrom; Nancy M Bauman; Yvonne E Chiu; Robert H Chun; Maria C Garzon; Kristen E Holland; Leonardo Liberman; Susan MacLellan-Tobert; Anthony J Mancini; Denise Metry; Katherine B Puttgen; Marcia Seefeldt; Robert Sidbury; Kendra M Ward; Francine Blei; Eulalia Baselga; Laura Cassidy; David H Darrow; Shawna Joachim; Eun-Kyung M Kwon; Kari Martin; Jonathan Perkins; Dawn H Siegel; Robert J Boucek; Ilona J Frieden
Journal:  Pediatrics       Date:  2012-12-24       Impact factor: 7.124

  9 in total
  8 in total

1.  Les anomalies vasculaires pendant l'enfance : quand traiter les patients et quand les diriger vers une ressource spécialisée.

Authors:  Kelley Zwicker; Julie Powell; Carl Cummings
Journal:  Paediatr Child Health       Date:  2022-08-22       Impact factor: 2.600

2.  Vascular anomalies in childhood: When to treat and when to refer.

Authors:  Kelley Zwicker; Julie Powell; Carl Cummings
Journal:  Paediatr Child Health       Date:  2022-08-22       Impact factor: 2.600

3.  Good Clinical Responders to Topical Timolol in Patients with Infantile Hemangiomas: A 7-Year Retrospective Study of 328 Korean Patients.

Authors:  Da-Ae Yu; Se Hee Min; Jaeryong Song; Jong Seo Park; Hanjae Lee; Jungyoon Ohn; Kyu Han Kim
Journal:  Ann Dermatol       Date:  2022-10       Impact factor: 0.722

Review 4.  Beta blockers: an innovation in the treatment of infantile hemangiomas.

Authors:  Shehla Admani; Stephanie Feldstein; Ernesto M Gonzalez; Sheila Fallon Friedlander
Journal:  J Clin Aesthet Dermatol       Date:  2014-07

5.  Intolerable side effects during propranolol therapy for infantile hemangioma: frequency, risk factors and management.

Authors:  Yi Ji; Siyuan Chen; Qi Wang; Bo Xiang; Zhicheng Xu; Lin Zhong; Kaiying Yang; Guoyan Lu; Liqin Qiu
Journal:  Sci Rep       Date:  2018-03-09       Impact factor: 4.379

6.  Deep coma in a child treated with propranolol for infantile hemangioma.

Authors:  Ilirjana Bakalli; Elmira Kola; Robert Lluka; Ermela Celaj; Durim Sala; Inva Gjeta; Sashenka Sallabanda; Dea Klironomi
Journal:  BMC Pediatr       Date:  2019-07-02       Impact factor: 2.125

Review 7.  Infantile Hemangioma: A Brief Review.

Authors:  Madalina Bota; Gheorghe Popa; Cristina Blag; Alexandru Tataru
Journal:  Clujul Med       Date:  2015-01-28

8.  Management of infantile hemangiomas during the COVID pandemic.

Authors:  Ilona J Frieden; Katherine B Püttgen; Beth A Drolet; Maria C Garzon; Sarah L Chamlin; Elena Pope; Anthony J Mancini; Christine T Lauren; Erin F Mathes; Dawn H Siegel; Deepti Gupta; Anita N Haggstrom; Megha M Tollefson; Eulalia Baselga; Kimberly D Morel; Sonal D Shah; Kristen E Holland; Denise M Adams; Kimberly A Horii; Brandon D Newell; Julie Powell; Catherine C McCuaig; Amy J Nopper; Denise W Metry; Sheilagh Maguiness
Journal:  Pediatr Dermatol       Date:  2020-05-16       Impact factor: 1.997

  8 in total

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