Literature DB >> 23313269

Triglyceride accumulation inhibitory effects of phenylpropanoid glycosides from Boschniakia rossica Fedtsch et Flerov.

Yi Zhang1, Chunhua Wu, Lingling Guo, Yue Chen, Lifeng Han, Erwei Liu, Xiumei Gao, Tao Wang.   

Abstract

Bioassay-guided fractionation led to isolation of five new phenylpropanol glycosides, rossicasides G (1), H (2), I (3), J (4), and K (5), together with seven known compounds (6-12) from Boschniakia rossica. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Activity screening results showed that some isolates had TG accumulation inhibitory effects in HepG2 cells. Furthermore, the structure-activity relationship was partly clarified.
Copyright © 2012. Published by Elsevier B.V.

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Year:  2013        PMID: 23313269     DOI: 10.1016/j.fitote.2012.12.031

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  3 in total

1.  Bioactive cyclolanstane-type saponins from the stems of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao.

Authors:  Tingting Wang; Jingya Ruan; Xiaoxia Li; Liping Chao; Pingping Shi; Lifeng Han; Yi Zhang; Tao Wang
Journal:  J Nat Med       Date:  2016-01-22       Impact factor: 2.343

2.  Polyphenols from the Peels of Punica granatum L. and Their Bioactivity of Suppressing Lipopolysaccharide-Stimulated Inflammatory Cytokines and Mediators in RAW 264.7 Cells via Activating p38 MAPK and NF-κB Signaling Pathways.

Authors:  Hui-Min Li; Ongher Kouye; Ding-Shan Yang; Ya-Qi Zhang; Jing-Ya Ruan; Li-Feng Han; Yi Zhang; Tao Wang
Journal:  Molecules       Date:  2022-07-20       Impact factor: 4.927

3.  BRP, a polysaccharide fraction isolated from Boschniakia rossica, protects against galactosamine and lipopolysaccharide induced hepatic failure in mice.

Authors:  Jishu Quan; Meihua Jin; Huixian Xu; Delai Qiu; Xuezhe Yin
Journal:  J Clin Biochem Nutr       Date:  2014-04-04       Impact factor: 3.114

  3 in total

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