| Literature DB >> 23311372 |
Abstract
We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution of different subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth equation is introduced to model the evolution of the moving boundary. The system includes non-local terms of integral type in the coefficients. Under some restrictions in the parameters we show that there exists a unique homogeneous steady state which is stable.Entities:
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Year: 2013 PMID: 23311372 DOI: 10.3934/mbe.2013.10.263
Source DB: PubMed Journal: Math Biosci Eng ISSN: 1547-1063 Impact factor: 2.080