Literature DB >> 23311372

On a mathematical model of tumor growth based on cancer stem cells.

J Ignacio Tello1.   

Abstract

We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution of different subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth equation is introduced to model the evolution of the moving boundary. The system includes non-local terms of integral type in the coefficients. Under some restrictions in the parameters we show that there exists a unique homogeneous steady state which is stable.

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Year:  2013        PMID: 23311372     DOI: 10.3934/mbe.2013.10.263

Source DB:  PubMed          Journal:  Math Biosci Eng        ISSN: 1547-1063            Impact factor:   2.080


  5 in total

Review 1.  Modeling head and neck cancer stem cell-mediated tumorigenesis.

Authors:  Alexander T Pearson; Trachette L Jackson; Jacques E Nör
Journal:  Cell Mol Life Sci       Date:  2016-05-05       Impact factor: 9.261

2.  A partial differential equation model and its reduction to an ordinary differential equation model for prostate tumor growth under intermittent hormone therapy.

Authors:  Youshan Tao; Qian Guo; Kazuyuki Aihara
Journal:  J Math Biol       Date:  2013-08-28       Impact factor: 2.259

3.  In silico study of the impact of cancer stem cell dynamics and radiobiological hypoxia on tumour response to hyperfractionated radiotherapy.

Authors:  L G Marcu; D Marcu; S M Filip
Journal:  Cell Prolif       Date:  2016-04-15       Impact factor: 6.831

4.  A mathematical model of cancer stem cell driven tumor initiation: implications of niche size and loss of homeostatic regulatory mechanisms.

Authors:  Sara N Gentry; Trachette L Jackson
Journal:  PLoS One       Date:  2013-08-19       Impact factor: 3.240

5.  Sampling from single-cell observations to predict tumor cell growth in-vitro and in-vivo.

Authors:  Alexander T Pearson; Patrick Ingram; Shoumei Bai; Patrick O'Hayer; Jaehoon Chung; Euisik Yoon; Trachette Jackson; Ronald J Buckanovich
Journal:  Oncotarget       Date:  2017-11-25
  5 in total

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