| Literature DB >> 23307984 |
Gregory P Kalemkerian, Wallace Akerley, Paul Bogner, Hossein Borghaei, Laura Qm Chow, Robert J Downey, Leena Gandhi, Apar Kishor P Ganti, Ramaswamy Govindan, John C Grecula, James Hayman, Rebecca Suk Heist, Leora Horn, Thierry Jahan, Marianna Koczywas, Billy W Loo, Robert E Merritt, Cesar A Moran, Harvey B Niell, Janis O'Malley, Jyoti D Patel, Neal Ready, Charles M Rudin, Charles C Williams, Kristina Gregory, Miranda Hughes.
Abstract
Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of recurrent disease. In patients with extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival in most patients; however, long-term survival is rare. Most cases of SCLC are attributable to cigarette smoking; therefore, smoking cessation should be strongly promoted.Entities:
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Year: 2013 PMID: 23307984 PMCID: PMC3715060 DOI: 10.6004/jnccn.2013.0011
Source DB: PubMed Journal: J Natl Compr Canc Netw ISSN: 1540-1405 Impact factor: 11.908