Literature DB >> 23307188

Obesity, metabolic factors, and colorectal adenomas: a retrospective study in a racially diverse New York State Hospital.

Seth Lipka1, Xi Emily Zheng, Jorge Hurtado-Cordovi, Jaspreet Singh, Evan Levine, Raymond Vlacancich, Bhuma Krishnamachari, Min-Kyung Jung, Shuang Fu, Umeko Takeshige, Boris Avezbakiyev, Ting Li, Javed Iqbal, Kaleem Rizvon, Paul Mustacchia.   

Abstract

OBJECTIVE: We studied a racially diverse population and the relationship with colorectal adenomas (CA) further looking for risks related to BMI and metabolic factors. DESIGNS: Seven hundred seventy-nine patients who underwent screening colonoscopies between 2007 and 2009 meeting exclusion criteria were included. To evaluate the association between race, BMI, and other metabolic factors with having one or more CA detected at colonoscopy, adjusted odds ratios and 95 % CI were estimated using unconditional logistic regression models. OUTCOMES: CA were detected in 167 out of 779 (21.4 %) patients. Compared to Whites, Hispanics were less likely to have one or more adenomas detected during a screening colonoscopy (OR = 0.52, 95 % CI, 0.31-0.88; p = 0.01). There was no significant statistical difference between Blacks and Whites, or other races and Whites. There was an association between the presence of CA and smoking (OR = 1.57, 95 % CI, 1.02-2.43; p = 0.04).
CONCLUSION: Our results showed that Hispanics were less likely to have an adenoma detected during a screening colonoscopy than Whites. No statistical significant difference was found between patients with metabolic factors and the presence of colorectal adenoma.

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Year:  2013        PMID: 23307188     DOI: 10.1007/s12029-013-9476-8

Source DB:  PubMed          Journal:  J Gastrointest Cancer


  35 in total

1.  Association of obesity, serum glucose and lipids with the risk of advanced colorectal adenoma and cancer: a case-control study in Korea.

Authors:  Y W Chung; D S Han; Y K Park; B K Son; C H Paik; H L Lee; Y C Jeon; J H Sohn
Journal:  Dig Liver Dis       Date:  2006-06-21       Impact factor: 4.088

2.  Characterization of the synergistic effect of insulin and transferrin and the regulation of their receptors on a human colon carcinoma cell line.

Authors:  L F Watkins; L R Lewis; A E Levine
Journal:  Int J Cancer       Date:  1990-02-15       Impact factor: 7.396

3.  Colorectal cancer mortality and factors related to the insulin resistance syndrome.

Authors:  Laura A Colangelo; Susan M Gapstur; Peter H Gann; Alan R Dyer; Kiang Liu
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2002-04       Impact factor: 4.254

Review 4.  Recent advances in understanding the role of diet and obesity in the development of colorectal cancer.

Authors:  Elizabeth K Lund; Nigel J Belshaw; Giles O Elliott; Ian T Johnson
Journal:  Proc Nutr Soc       Date:  2011-03-09       Impact factor: 6.297

5.  Metabolic syndrome components and colorectal adenoma in the CLUE II cohort.

Authors:  Konstantinos K Tsilidis; Frederick L Brancati; Michael N Pollak; Nader Rifai; Sandra L Clipp; Judith Hoffman-Bolton; Kathy J Helzlsouer; Elizabeth A Platz
Journal:  Cancer Causes Control       Date:  2009-09-23       Impact factor: 2.506

6.  Risk factors for advanced colonic neoplasia and hyperplastic polyps in asymptomatic individuals.

Authors:  David A Lieberman; Sheila Prindiville; David G Weiss; Walter Willett
Journal:  JAMA       Date:  2003-12-10       Impact factor: 56.272

7.  Adiposity in relation to colorectal adenomas and hyperplastic polyps in women.

Authors:  Michael F Leitzmann; Andrew Flood; Leah M Ferrucci; Philip Schoenfeld; Brooks Cash; Arthur Schatzkin; Amanda J Cross
Journal:  Cancer Causes Control       Date:  2009-04-22       Impact factor: 2.506

8.  Do factors related to endogenous and exogenous estrogens modify the relationship between obesity and risk of colorectal adenomas in women?

Authors:  Lesley A Wolf; Paul D Terry; John D Potter; Roberd M Bostick
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2007-04       Impact factor: 4.254

9.  Lifestyle as a predictor for colonic neoplasia in asymptomatic individuals.

Authors:  Inger K Larsen; Tom Grotmol; Kari Almendingen; Geir Hoff
Journal:  BMC Gastroenterol       Date:  2006-01-13       Impact factor: 3.067

10.  An association between colonic adenoma and abdominal obesity: a cross-sectional study.

Authors:  Youngjoo Kim; Yunjin Kim; Sangyeoup Lee
Journal:  BMC Gastroenterol       Date:  2009-01-15       Impact factor: 3.067

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  4 in total

1.  Screening colonoscopy in the initial workup of bariatric surgery patients: guidelines are needed.

Authors:  Mohammed Al Hadad; Nidal Dehni; Abdullah Alakhras; Yalda Ziaei; Nicolas P Turrin; Abdelrahman Nimeri
Journal:  Surg Endosc       Date:  2014-01-08       Impact factor: 4.584

2.  Ethnic disparities in the risk of colorectal adenomas associated with lipid levels: a retrospective multiethnic study.

Authors:  Ashley H Davis-Yadley; Seth Lipka; Huafeng Shen; Valerie Devanney; Supreeya Swarup; Alex Barnowsky; Jeff Silpe; Josh Mosdale; Qinshi Pan; Svetlana Fridlyand; Suhas Sreeharshan; Albin Abraham; Prakash Viswanathan; Bhuma Krishnamachari
Journal:  J Gastrointest Cancer       Date:  2015-03

3.  Association between investigator-measured body-mass index and colorectal adenoma: a systematic review and meta-analysis of 168,201 subjects.

Authors:  Martin Chi-Sang Wong; Chun-Hei Chan; Wilson Cheung; Din-Hei Fung; Miaoyin Liang; Jason Li-Wen Huang; Yan-Hong Wang; Johnny Yu Jiang; Chun-Pong Yu; Harry Haoxiang Wang; Justin Che-Yuen Wu; Francis Ka-Leung Chan; Joseph Jao-Yiu Sung
Journal:  Eur J Epidemiol       Date:  2017-12-29       Impact factor: 8.082

4.  BMI and the risk of colorectal adenoma in African-Americans.

Authors:  Hassan Ashktorab; Mansour Paydar; Shahla Yazdi; Hassan Hassanzadeh Namin; Andrew Sanderson; Rehana Begum; Mohammad Semati; Firoozeh Etaati; Edward Lee; Hassan Brim; Anteneh Zenebe; Gail Nunlee-Bland; Adeyinka O Laiyemo; Mehdi Nouraie
Journal:  Obesity (Silver Spring)       Date:  2014-02-11       Impact factor: 5.002

  4 in total

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