Na Young Lee1, Hye Jin Chung, Chan Kee Park. 1. Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #505 Banpo-dong, Seocho-gu, Seoul 137-040, Korea.
Abstract
PURPOSE: To compare Heidelberg retinal tomography (HRT) 3 and frequency-doubling technology (FDT) perimetry for diagnosis of glaucoma. METHODS: One eye of each of 117 patients was randomly chosen. The eyes were imaged by HRT3 and tested by FDT. The pattern standard deviation (PSD) and global glaucoma probability score (GPS) were selected as representative output, and sensitivity, specificity, positive predictive value, and negative predictive value determined for each. The agreement between the 2 diagnostic methods was analyzed. RESULTS: The sensitivity and specificity of HRT3 and FDT perimetry for PSD (65.4 and 62.7 %, respectively) and for GPS (69.2 and 62.7 %, respectively) were similar, as were the positive predictive values (PSD 40.5 %, GPS 41.9 %). However, the 2 methods had only slight diagnostic agreement (κ = 0.112), and this was not significant (P = 0.281). CONCLUSIONS: FDT perimetry and HRT3 had no significant diagnostic agreement. Thus, the results from both examinations should be considered when determining diagnosis of glaucoma.
RCT Entities:
PURPOSE: To compare Heidelberg retinal tomography (HRT) 3 and frequency-doubling technology (FDT) perimetry for diagnosis of glaucoma. METHODS: One eye of each of 117 patients was randomly chosen. The eyes were imaged by HRT3 and tested by FDT. The pattern standard deviation (PSD) and global glaucoma probability score (GPS) were selected as representative output, and sensitivity, specificity, positive predictive value, and negative predictive value determined for each. The agreement between the 2 diagnostic methods was analyzed. RESULTS: The sensitivity and specificity of HRT3 and FDT perimetry for PSD (65.4 and 62.7 %, respectively) and for GPS (69.2 and 62.7 %, respectively) were similar, as were the positive predictive values (PSD 40.5 %, GPS 41.9 %). However, the 2 methods had only slight diagnostic agreement (κ = 0.112), and this was not significant (P = 0.281). CONCLUSIONS: FDT perimetry and HRT3 had no significant diagnostic agreement. Thus, the results from both examinations should be considered when determining diagnosis of glaucoma.
Authors: Michele Iester; Carlo E Traverso; Fabio De Feo; Giuseppe Sanna; Michele Altieri; Paolo Vittone; Giovanni Calabria Journal: J Glaucoma Date: 2005-10 Impact factor: 2.503