Ocular microtremor measurement using laser-speckle metrology.

We describe a novel, noninvasive measurement approach for recording a small involuntary tremor of the eye known as ocular microtremor. The method is based on measuring out-of-plane angular displacements of a target by using laser-speckle correlation of images recorded in the Fourier plane of a lens. The system has a dynamic range of 4 to 5000 μrad, resolution of 4 μrad, and a bandwidth of 250 Hz. The design and optimization of the system is presented with an in vitro validation of the system against its specification.