PURPOSE: This study sought to identify and characterize major patterns of functional aging based on activities of daily living (ADL). METHODS: We followed 754 community-living adults aged 70 years or older monthly for ADLs, instrumental ADLs, hospitalization and restricted activity over 10 years. A generalized growth mixture model was used to identify trajectories of ADL disability across seven 18-month intervals. Cumulative burdens of disability and morbidity from different trajectories were examined using a generalized estimating equation Poisson model. RESULTS: Five distinct trajectories emerged. The predominant trajectory maintained ADL independence, with membership probability being 61.6%. The remaining trajectories either stayed at low (1 or 2 ADLs, 13.6%) or high (3 or 4 ADLs, 7.0%) levels of disability or declined gradually toward low (11.2%) or high (6.5%) disability. The independent trajectory was associated with the lowest burdens of disability and morbidity and a decreasing time trend of restricted activity, whereas the high disability trajectory demonstrated opposite trends. About 31% of the cohort remained in the same trajectory throughout the follow-up period. CONCLUSIONS: The course of functional aging is heterogeneous and dynamic. Although most older adults maintain functional autonomy, some may experience persistent disability or progress toward severe disability with substantial morbidity.
PURPOSE: This study sought to identify and characterize major patterns of functional aging based on activities of daily living (ADL). METHODS: We followed 754 community-living adults aged 70 years or older monthly for ADLs, instrumental ADLs, hospitalization and restricted activity over 10 years. A generalized growth mixture model was used to identify trajectories of ADL disability across seven 18-month intervals. Cumulative burdens of disability and morbidity from different trajectories were examined using a generalized estimating equation Poisson model. RESULTS: Five distinct trajectories emerged. The predominant trajectory maintained ADL independence, with membership probability being 61.6%. The remaining trajectories either stayed at low (1 or 2 ADLs, 13.6%) or high (3 or 4 ADLs, 7.0%) levels of disability or declined gradually toward low (11.2%) or high (6.5%) disability. The independent trajectory was associated with the lowest burdens of disability and morbidity and a decreasing time trend of restricted activity, whereas the high disability trajectory demonstrated opposite trends. About 31% of the cohort remained in the same trajectory throughout the follow-up period. CONCLUSIONS: The course of functional aging is heterogeneous and dynamic. Although most older adults maintain functional autonomy, some may experience persistent disability or progress toward severe disability with substantial morbidity.
Authors: Douglas A Wolf; Vicki A Freedman; Jan I Ondrich; Christopher L Seplaki; Brenda C Spillman Journal: J Gerontol B Psychol Sci Soc Sci Date: 2015-03-03 Impact factor: 4.077
Authors: Leslie Vaughan; Xiaoyan Leng; Michael J La Monte; Hilary A Tindle; Barbara B Cochrane; Sally A Shumaker Journal: J Gerontol A Biol Sci Med Sci Date: 2016-03 Impact factor: 6.053
Authors: Anna H Chodos; Margot B Kushel; S Ryan Greysen; David Guzman; Eric R Kessell; Urmimala Sarkar; L Elizabeth Goldman; Jeffrey M Critchfield; Edgar Pierluissi Journal: J Gen Intern Med Date: 2015-12 Impact factor: 5.128