Literature DB >> 233046

The heart in diabetes mellitus. Part I. Biochemical basis for myocardial dysfunction.

L H Opie, M J Tansey, B M Kennelly.   

Abstract

The heart in acutely diabetic animals is subject to multiple inhibitions of glucose metabolism caused by enhanced metabolism of free fatty acids (FFA) and ketone bodies. Such metabolic changes may impair the reaction of the diabetic heart to oxygen lack. In chronically diabetic hearts the increased deposition of triglycerides in the heart and the formation of glycoproteins may underlie the newly recognized clinical entity of diabetic cardiomyopathy.

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Year:  1979        PMID: 233046

Source DB:  PubMed          Journal:  S Afr Med J


  4 in total

Review 1.  Mechanisms of subcellular remodeling in heart failure due to diabetes.

Authors:  Naranjan S Dhalla; Nobuakira Takeda; Delfin Rodriguez-Leyva; Vijayan Elimban
Journal:  Heart Fail Rev       Date:  2014-01       Impact factor: 4.214

2.  Glycolysis and glucose oxidation in the rat heart under nonrecirculating perfusion conditions.

Authors:  P Rösen; M Adrian; J Feuerstein; H Reinauer
Journal:  Basic Res Cardiol       Date:  1984 May-Jun       Impact factor: 17.165

3.  Inhibition by adenosine triphosphate of heart microsomal neutral lipase activity.

Authors:  V K Murthy; M R Stiles; J C Shipp
Journal:  Lipids       Date:  1983-06       Impact factor: 1.880

4.  Coronary blood flow in chronic insulin-dependent diabetic dogs.

Authors:  K W Small; E Stefansson; D L Hatchell
Journal:  Acta Diabetol Lat       Date:  1989 Oct-Dec
  4 in total

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