Literature DB >> 23304367

Learning medical diagnosis models from multiple experts.

Hamed Valizadegan1, Quang Nguyen, Milos Hauskrecht.   

Abstract

Building classification models from clinical data often requires labeling examples by human experts. However, it is difficult to obtain a perfect set of labels everyone agrees on because medical data are typically very complicated and it is quite common that different experts have different opinions on the same patient data. A solution that has been recently explored by the research community is learning from multiple experts/annotators. The objective of learning from multiple experts is to model different characteristics of the human experts and combine them to obtain a consensus model. In this work, we study and develop a new probabilistic approach for learning classification models from labels provided by multiple experts. Our method explicitly models and incorporates three characteristics of annotators into the learning process: their specific prediction model, consistency and bias. We show that in addition to building a superior classification model, our method also helps to model behavior of annotators. We applied the proposed method to learn different characteristics of Physicians labeling clinical records for Heparin Induced Thrombocytopenia (HIT) and combine them in order to obtain a final classifier.

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Year:  2012        PMID: 23304367      PMCID: PMC3540500     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  3 in total

Review 1.  Heparin-induced thrombocytopenia: pathogenesis and management.

Authors:  Theodore E Warkentin
Journal:  Br J Haematol       Date:  2003-05       Impact factor: 6.998

2.  Feature importance analysis for patient management decisions.

Authors:  Michal Valko; Milos Hauskrecht
Journal:  Stud Health Technol Inform       Date:  2010

3.  Impact of the patient population on the risk for heparin-induced thrombocytopenia.

Authors:  T E Warkentin; J A Sheppard; P Horsewood; P J Simpson; J C Moore; J G Kelton
Journal:  Blood       Date:  2000-09-01       Impact factor: 22.113

  3 in total
  1 in total

1.  Learning by aggregating experts and filtering novices: a solution to crowdsourcing problems in bioinformatics.

Authors:  Ping Zhang; Weidan Cao; Zoran Obradovic
Journal:  BMC Bioinformatics       Date:  2013-09-24       Impact factor: 3.169

  1 in total

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