OBJECTIVES: This study aimed to explore the period between onset of pain and hospital-admission (pain-to-admission time) in patients with acute pancreatitis (AP), to investigate the prognostic value and associated factors of this time, and to ascertain the knowledge about the pancreas in these patients. METHODS: An analysis of a prospective multicenter study was done, which included 188 patients with AP. RESULTS: Median pain-to-admission time was 27 hours (interquartile range, 6.0-72.0). Median pain-to-admission time was significantly shorter in intensive care unit (ICU) patients (10 hours) compared to non-ICU patients (36 hours) (P = 0.045). Short pain-to-admission time was associated with high pain level. Median pain level (0, no pain; 10, maximal pain) was 8.0 (interquartile range, 7.0-10.0). Older age correlated with lower pain level (r = -0.26; P = 0.002). Multiple logistic regression analysis including the admission values for serum lipase and C-reactive protein and the corresponding interactions to the pain-to-admission time showed substantial discriminative ability regarding ICU admission (concordance index, 0.706; P = 0.006). 86% (112/130) knew that they have a pancreas, 72% (81/112) of these patients knew that AP exists, and 56% (45/81) recognized that AP is potentially fatal. CONCLUSIONS: Knowledge about AP in hospitalized AP patients is poor. Serum lipase and C-reactive protein in dependency of the pain-to-admission time might be a suitable predictor for severity of AP.
OBJECTIVES: This study aimed to explore the period between onset of pain and hospital-admission (pain-to-admission time) in patients with acute pancreatitis (AP), to investigate the prognostic value and associated factors of this time, and to ascertain the knowledge about the pancreas in these patients. METHODS: An analysis of a prospective multicenter study was done, which included 188 patients with AP. RESULTS: Median pain-to-admission time was 27 hours (interquartile range, 6.0-72.0). Median pain-to-admission time was significantly shorter in intensive care unit (ICU) patients (10 hours) compared to non-ICU patients (36 hours) (P = 0.045). Short pain-to-admission time was associated with high pain level. Median pain level (0, no pain; 10, maximal pain) was 8.0 (interquartile range, 7.0-10.0). Older age correlated with lower pain level (r = -0.26; P = 0.002). Multiple logistic regression analysis including the admission values for serum lipase and C-reactive protein and the corresponding interactions to the pain-to-admission time showed substantial discriminative ability regarding ICU admission (concordance index, 0.706; P = 0.006). 86% (112/130) knew that they have a pancreas, 72% (81/112) of these patients knew that AP exists, and 56% (45/81) recognized that AP is potentially fatal. CONCLUSIONS: Knowledge about AP in hospitalized AP patients is poor. Serum lipase and C-reactive protein in dependency of the pain-to-admission time might be a suitable predictor for severity of AP.
Authors: Navamayooran Thavanesan; Sophie White; Shiela Lee; Bathiya Ratnayake; Kofi W Oppong; Manu K Nayar; Linda Sharp; Asbjørn Mohr Drewes; Gabriele Capurso; Enrique De-Madaria; Ajith K Siriwardena; John A Windsor; Sanjay Pandanaboyana Journal: World J Surg Date: 2022-01-07 Impact factor: 3.282
Authors: Mária Földi; Noémi Gede; Szabolcs Kiss; Áron Vincze; Judit Bajor; Imre Szabó; Zoltán Szepes; Ferenc Izbéki; Judit Gervain; József Hamvas; Zsuzsanna Vitális; Eszter Fehér; Stefan Crai; Ville Sallinen; Elena Ramirez-Maldonado; Ágnes Meczker; Péter Varjú; Goran Poropat; Davor Stimac; Nándor Faluhelyi; Attila Miseta; Tamás Nagy; Zsolt Márton; András Vereczkei; Péter Jenő Hegyi; Andrea Párniczky; Péter Hegyi; Andrea Szentesi Journal: Eur J Pain Date: 2021-11-16 Impact factor: 3.651
Authors: Sebastian Rasch; Veit Phillip; Stephanie Reichel; Bettina Rau; Christian Zapf; Jonas Rosendahl; Ulrich Halm; Markus Zachäus; Martin Müller; Alexander Kleger; Albrecht Neesse; Jochen Hampe; Mark Ellrichmann; Felix Rückert; Peter Strauß; Alexander Arlt; Volker Ellenrieder; Thomas M Gress; Werner Hartwig; Ernst Klar; Joachim Mössner; Stefan Post; Roland M Schmid; Thomas Seufferlein; Marco Siech; Jens Werner; Uwe Will; Hana Algül Journal: PLoS One Date: 2016-09-26 Impact factor: 3.240