Literature DB >> 23297615

[Iodine and thyroid gland with or without nuclear catastrophe].

Ljiljana Todorović Dilas1, Ivana Bajkin, Tijana Icin, Jovanka Novaković Paro, Branka Kovacev Zavisić.   

Abstract

INTRODUCTION: Iodine, as a trace element, is a necessary and limiting substrate for thyroid gland hormone synthesis. It is an essential element that enables the thyroid gland to produce thyroid hormones thyroxine (T4) and triiodothyronine (T3). Synthesis of Thyroid Hormones and Iodine Metabolism. Three iodine molecules are added to make triiodothyronine, and four for thyroxine - the two key hormones produced by the thyroid gland. Iodine deficiency The proper daily amount of iodine is required for optimal thyroid function. Iodine deficiency can cause hypothyroidism, developmental brain disorders and goiter. Iodine deficiency is the single most common cause of preventable mental retardation and brain damage in the world. It also decreases child survival, causes goiters, and impairs growth and development. Iodine deficiency disorders in pregnant women cause miscarriages, stillbirths, and other complications. Children with iodine deficiency disorders can grow up stunted, apathetic, mentally retarded, and incapable of normal movements, speech or hearing. Excessive Iodine Intake. Excessive iodine intake, which can trigger a utoimmune thyroid disease and dysfunction. is on the other side. Iodine use in Case of Nuclear Catastrophe. In addition to other severe consuquences of radioactivity, high amount of radioactive iodine causes significant increase in incidence of thyroid gland carcinoma after some of the nuclear catastrophes (Hiroshima, Nagasaki, Chernobyl, Fukushima). The incidence of thyroid carcinoma was increased mostly in children. This paper was aimed at clarifying some of the possibilities of prevention according to the recommendations given by the World Health Organization.

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Year:  2012        PMID: 23297615     DOI: 10.2298/mpns1212489t

Source DB:  PubMed          Journal:  Med Pregl        ISSN: 0025-8105


  4 in total

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Journal:  Radiol Med       Date:  2019-11-05       Impact factor: 3.469

2.  Molecular profiling of papillary thyroid carcinomas in healthcare workers exposed to low dose radiation at the workplace.

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Review 3.  Radiation and Thyroid Cancer.

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Journal:  Int J Mol Sci       Date:  2017-04-26       Impact factor: 5.923

4.  Inherited variants in genes somatically mutated in thyroid cancer.

Authors:  Chiara Campo; Aleksandra Köhler; Gisella Figlioli; Rossella Elisei; Cristina Romei; Monica Cipollini; Franco Bambi; Kari Hemminki; Federica Gemignani; Stefano Landi; Asta Försti
Journal:  PLoS One       Date:  2017-04-14       Impact factor: 3.240

  4 in total

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