Literature DB >> 23296730

Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining.

Reza Khorooshi1, Trevor Owens.   

Abstract

Phosphorylation of signal transducers and activators of transcription (STATs) indicates their involvement in active signaling. Here we describe immunohistochemical staining procedures for detection and identification of the cellular localization of phospho-STAT2 in the central nervous system (CNS) of mice. The procedures include single and dual/triple labeling immunostaining of phospho-STAT2 in the hippocampus of mice following entorhinal cortex lesion.

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Year:  2013        PMID: 23296730     DOI: 10.1007/978-1-62703-242-1_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  4 in total

1.  Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis.

Authors:  Reza Khorooshi; Marlene Thorsen Mørch; Thomas Hellesøe Holm; Carsten Tue Berg; Ruthe Truong Dieu; Dina Dræby; Shohreh Issazadeh-Navikas; Siegfried Weiss; Stefan Lienenklaus; Trevor Owens
Journal:  Acta Neuropathol       Date:  2015-04-14       Impact factor: 17.088

2.  A novel microglial subset plays a key role in myelinogenesis in developing brain.

Authors:  Agnieszka Wlodarczyk; Inge R Holtman; Martin Krueger; Nir Yogev; Julia Bruttger; Reza Khorooshi; Anouk Benmamar-Badel; Jelkje J de Boer-Bergsma; Nellie A Martin; Khalad Karram; Isabella Kramer; Erik Wgm Boddeke; Ari Waisman; Bart Jl Eggen; Trevor Owens
Journal:  EMBO J       Date:  2017-09-28       Impact factor: 11.598

3.  Selective localization of IgG from cerebrospinal fluid to brain parenchyma.

Authors:  Marlene Thorsen Mørch; Sofie Forsberg Sørensen; Reza Khorooshi; Nasrin Asgari; Trevor Owens
Journal:  J Neuroinflammation       Date:  2018-04-17       Impact factor: 8.322

4.  Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation.

Authors:  Agnieszka Wlodarczyk; Oriane Cédile; Kirstine Nolling Jensen; Agathe Jasson; Jyothi Thyagabhavan Mony; Reza Khorooshi; Trevor Owens
Journal:  Front Immunol       Date:  2015-09-08       Impact factor: 7.561

  4 in total

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