Literature DB >> 23296651

Markers of cellular senescence.

Amancio Carnero1.   

Abstract

Cellular senescence is a tumor suppression mechanism that evolved to limit duplication in somatic cells. Senescence is imposed by natural replicative boundaries or stress-induced signals, such as oncogenic transformation. Neoplastic cells can be forced to undergo senescence through genetic manipulations and epigenetic factors, including anticancer drugs, radiation, and differentiating agents. Senescent cells show distinct phenotypic and molecular characteristics, both in vitro or in vivo. These biomarkers might either cause or result from senescence induction, but could also be the byproducts of physiological changes in these non-replicating cells.

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Year:  2013        PMID： 23296651     DOI： 10.1007/978-1-62703-239-1_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  24 in total

Review 1.  Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:  William H Goodson; Leroy Lowe; David O Carpenter; Michael Gilbertson; Abdul Manaf Ali; Adela Lopez de Cerain Salsamendi; Ahmed Lasfar; Amancio Carnero; Amaya Azqueta; Amedeo Amedei; Amelia K Charles; Andrew R Collins; Andrew Ward; Anna C Salzberg; Annamaria Colacci; Ann-Karin Olsen; Arthur Berg; Barry J Barclay; Binhua P Zhou; Carmen Blanco-Aparicio; Carolyn J Baglole; Chenfang Dong; Chiara Mondello; Chia-Wen Hsu; Christian C Naus; Clement Yedjou; Colleen S Curran; Dale W Laird; Daniel C Koch; Danielle J Carlin; Dean W Felsher; Debasish Roy; Dustin G Brown; Edward Ratovitski; Elizabeth P Ryan; Emanuela Corsini; Emilio Rojas; Eun-Yi Moon; Ezio Laconi; Fabio Marongiu; Fahd Al-Mulla; Ferdinando Chiaradonna; Firouz Darroudi; Francis L Martin; Frederik J Van Schooten; Gary S Goldberg; Gerard Wagemaker; Gladys N Nangami; Gloria M Calaf; Graeme Williams; Gregory T Wolf; Gudrun Koppen; Gunnar Brunborg; H Kim Lyerly; Harini Krishnan; Hasiah Ab Hamid; Hemad Yasaei; Hideko Sone; Hiroshi Kondoh; Hosni K Salem; Hsue-Yin Hsu; Hyun Ho Park; Igor Koturbash; Isabelle R Miousse; A Ivana Scovassi; James E Klaunig; Jan Vondráček; Jayadev Raju; Jesse Roman; John Pierce Wise; Jonathan R Whitfield; Jordan Woodrick; Joseph A Christopher; Josiah Ochieng; Juan Fernando Martinez-Leal; Judith Weisz; Julia Kravchenko; Jun Sun; Kalan R Prudhomme; Kannan Badri Narayanan; Karine A Cohen-Solal; Kim Moorwood; Laetitia Gonzalez; Laura Soucek; Le Jian; Leandro S D'Abronzo; Liang-Tzung Lin; Lin Li; Linda Gulliver; Lisa J McCawley; Lorenzo Memeo; Louis Vermeulen; Luc Leyns; Luoping Zhang; Mahara Valverde; Mahin Khatami; Maria Fiammetta Romano; Marion Chapellier; Marc A Williams; Mark Wade; Masoud H Manjili; Matilde E Lleonart; Menghang Xia; Michael J Gonzalez; Michalis V Karamouzis; Micheline Kirsch-Volders; Monica Vaccari; Nancy B Kuemmerle; Neetu Singh; Nichola Cruickshanks; Nicole Kleinstreuer; Nik van Larebeke; Nuzhat Ahmed; Olugbemiga Ogunkua; P K Krishnakumar; Pankaj Vadgama; Paola A Marignani; Paramita M Ghosh; Patricia Ostrosky-Wegman; Patricia A Thompson; Paul Dent; Petr Heneberg; Philippa Darbre; Po Sing Leung; Pratima Nangia-Makker; Qiang Shawn Cheng; R Brooks Robey; Rabeah Al-Temaimi; Rabindra Roy; Rafaela Andrade-Vieira; Ranjeet K Sinha; Rekha Mehta; Renza Vento; Riccardo Di Fiore; Richard Ponce-Cusi; Rita Dornetshuber-Fleiss; Rita Nahta; Robert C Castellino; Roberta Palorini; Roslida Abd Hamid; Sabine A S Langie; Sakina E Eltom; Samira A Brooks; Sandra Ryeom; Sandra S Wise; Sarah N Bay; Shelley A Harris; Silvana Papagerakis; Simona Romano; Sofia Pavanello; Staffan Eriksson; Stefano Forte; Stephanie C Casey; Sudjit Luanpitpong; Tae-Jin Lee; Takemi Otsuki; Tao Chen; Thierry Massfelder; Thomas Sanderson; Tiziana Guarnieri; Tove Hultman; Valérian Dormoy; Valerie Odero-Marah; Venkata Sabbisetti; Veronique Maguer-Satta; W Kimryn Rathmell; Wilhelm Engström; William K Decker; William H Bisson; Yon Rojanasakul; Yunus Luqmani; Zhenbang Chen; Zhiwei Hu
Journal:  Carcinogenesis       Date:  2015-06       Impact factor: 4.944

Review 2.  Cellular senescence: a hitchhiker's guide.

Authors:  Aloysious Aravinthan
Journal:  Hum Cell       Date:  2015-02-18       Impact factor: 4.174

3.  The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines.

Authors:  Patrick M Perrigue; Michael E Silva; Charles D Warden; Nathan L Feng; Michael A Reid; Daniel J Mota; Lauren P Joseph; Yangzi Isabel Tian; Carlotta A Glackin; Margarita Gutova; Joseph Najbauer; Karen S Aboody; Michael E Barish
Journal:  Mol Cancer Res       Date:  2015-02-04       Impact factor: 5.852

4.  Nesprin-1 impact on tumorigenic cell phenotypes.

Authors:  Ilknur Sur-Erdem; Muhammed Sajid Hussain; Maria Asif; Nareg Pınarbası; Ali Cenk Aksu; Angelika A Noegel
Journal:  Mol Biol Rep       Date:  2019-11-18       Impact factor: 2.316

Review 5.  Are there roles for brain cell senescence in aging and neurodegenerative disorders?

Authors:  Florence C C Tan; Emmette R Hutchison; Erez Eitan; Mark P Mattson
Journal:  Biogerontology       Date:  2014-10-11       Impact factor: 4.277

Review 6.  Disruptive chemicals, senescence and immortality.

Authors:  Amancio Carnero; Carmen Blanco-Aparicio; Hiroshi Kondoh; Matilde E Lleonart; Juan Fernando Martinez-Leal; Chiara Mondello; A Ivana Scovassi; William H Bisson; Amedeo Amedei; Rabindra Roy; Jordan Woodrick; Annamaria Colacci; Monica Vaccari; Jayadev Raju; Fahd Al-Mulla; Rabeah Al-Temaimi; Hosni K Salem; Lorenzo Memeo; Stefano Forte; Neetu Singh; Roslida A Hamid; Elizabeth P Ryan; Dustin G Brown; John Pierce Wise; Sandra S Wise; Hemad Yasaei
Journal:  Carcinogenesis       Date:  2015-06       Impact factor: 4.944

7.  Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation.

Authors:  Mehtap Kilic Eren; Ayten Kilincli; Özkan Eren
Journal:  PLoS One       Date:  2015-04-29       Impact factor: 3.240

8.  Phosphorylation of gH2AX as a novel prognostic biomarker for laryngoesophageal dysfunction-free survival.

Authors:  María José de Miguel-Luken; Manuel Chaves-Conde; Begoña Quintana; Alicia Menoyo; Isabel Tirado; Verónica de Miguel-Luken; Jerónimo Pachón; David Chinchón; Vladimir Suarez; Amancio Carnero
Journal:  Oncotarget       Date:  2016-05-31

9.  Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.

Authors:  Tamas Kiss; Ádám Nyúl-Tóth; Priya Balasubramanian; Stefano Tarantini; Chetan Ahire; Jordan DelFavero; Andriy Yabluchanskiy; Tamas Csipo; Eszter Farkas; Graham Wiley; Lori Garman; Anna Csiszar; Zoltan Ungvari
Journal:  Geroscience       Date:  2020-03-31       Impact factor: 7.713

10.  Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology.

Authors:  Yanling Hu; Gemma L Fryatt; Mohammadmersad Ghorbani; Juliane Obst; David A Menassa; Maria Martin-Estebane; Tim A O Muntslag; Adrian Olmos-Alonso; Monica Guerrero-Carrasco; Daniel Thomas; Mark S Cragg; Diego Gomez-Nicola
Journal:  Cell Rep       Date:  2021-06-08       Impact factor: 9.423
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