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Literature DB >> 23296390

Osteoarthritis in 2012: Parallel evolution of OA phenotypes and therapies.

Abstract

2012 has witnessed new developments in targeted therapies for osteoarthritis, and in ways to identify those patients who might benefit most from their application. Together, these advances could go some way to addressing the urgent need for disease-modifying treatments for this common disease.

Entities: Disease Species

Mesh：

Substances：

Year: 2013 PMID： 23296390 DOI： 10.1038/nrrheum.2012.225

Source DB: PubMed Journal: Nat Rev Rheumatol ISSN： 1759-4790 Impact factor: 20.543

10 in total

Review 1. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis.

Authors: Jérémie Sellam; Francis Berenbaum
Journal: Nat Rev Rheumatol Date: 2010-10-05 Impact factor: 20.543

Review 2. OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009.

Authors: W Zhang; G Nuki; R W Moskowitz; S Abramson; R D Altman; N K Arden; S Bierma-Zeinstra; K D Brandt; P Croft; M Doherty; M Dougados; M Hochberg; D J Hunter; K Kwoh; L S Lohmander; P Tugwell
Journal: Osteoarthritis Cartilage Date: 2010-02-11 Impact factor: 6.576

3. In erosive hand osteoarthritis more inflammatory signs on ultrasound are found than in the rest of hand osteoarthritis.

Authors: Marion C Kortekaas; Wing-Yee Kwok; Monique Reijnierse; Tom W J Huizinga; Margreet Kloppenburg
Journal: Ann Rheum Dis Date: 2012-07-20 Impact factor: 19.103

Review 4. Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells.

Authors: Deborah Studer; Christopher Millan; Ece Öztürk; Katharina Maniura-Weber; Marcy Zenobi-Wong
Journal: Eur Cell Mater Date: 2012-07-24 Impact factor: 3.942

5. A stem cell-based approach to cartilage repair.

Authors: Kristen Johnson; Shoutian Zhu; Matthew S Tremblay; Joshua N Payette; Jianing Wang; Laure C Bouchez; Shelly Meeusen; Alana Althage; Charles Y Cho; Xu Wu; Peter G Schultz
Journal: Science Date: 2012-04-05 Impact factor: 47.728

6. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial.

Authors: Laura Louise Laslett; Dawn A Doré; Stephen J Quinn; Philippa Boon; Emma Ryan; Tania Maree Winzenberg; Graeme Jones
Journal: Ann Rheum Dis Date: 2012-02-21 Impact factor: 19.103

Review 7. Imaging the painful osteoarthritic knee joint: what have we learned?

Authors: Claire Y J Wenham; Philip G Conaghan
Journal: Nat Clin Pract Rheumatol Date: 2009-03

8. Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study).

Authors: Ali Guermazi; Jingbo Niu; Daichi Hayashi; Frank W Roemer; Martin Englund; Tuhina Neogi; Piran Aliabadi; Christine E McLennan; David T Felson
Journal: BMJ Date: 2012-08-29

9. Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification.

Authors: Gust Verbruggen; Ruth Wittoek; Bert Vander Cruyssen; Dirk Elewaut
Journal: Ann Rheum Dis Date: 2011-11-29 Impact factor: 19.103

10. Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee.

Authors: Walter P Maksymowych; Anthony S Russell; Peter Chiu; Alex Yan; Niall Jones; Tracey Clare; Robert G W Lambert
Journal: Arthritis Res Ther Date: 2012-10-04 Impact factor: 5.156

10 in total

12 in total

1. Reflecting on pain management for patients with osteoarthritis and other rheumatic disorders: there's more to pain management than managing pain.

Authors: Danielle Perret; Eric Y Chang; Winnie Pang; Shuntaro Shinada; Richard S Panush
Journal: Pain Manag Date: 2013-07

Osteoarthritis in 2012: Parallel evolution of OA phenotypes and therapies.

Review 1. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis.

Review 2. OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009.

3. In erosive hand osteoarthritis more inflammatory signs on ultrasound are found than in the rest of hand osteoarthritis.

Review 4. Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells.

5. A stem cell-based approach to cartilage repair.

6. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial.

Review 7. Imaging the painful osteoarthritic knee joint: what have we learned?

8. Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study).

9. Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification.

10. Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee.

1. Reflecting on pain management for patients with osteoarthritis and other rheumatic disorders: there's more to pain management than managing pain.

Review 2. Proliferative injection therapy for osteoarthritis: a systematic review.

Review 3. Emerging targets in osteoarthritis therapy.

Review 4. Cartilage damage in osteoarthritis and rheumatoid arthritis--two unequal siblings.

5. The Need for Predictive, Prognostic, Objective and Complementary Blood-Based Biomarkers in Osteoarthritis (OA).

6. Mathematical modelling of cytokines, MMPs and fibronectin fragments in osteoarthritic cartilage.

Review 7. On the predictive utility of animal models of osteoarthritis.

8. Biomarkers of (osteo)arthritis.

9. Injectable nanohydroxyapatite-chitosan-gelatin micro-scaffolds induce regeneration of knee subchondral bone lesions.

10. Sanguinarine protects against osteoarthritis by suppressing the expression of catabolic proteases.