Literature DB >> 23296004

Alzheimer's γ-secretase under arrestin.

Michael S Wolfe.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23296004     DOI： 10.1038/nm.3053

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


× No keyword cloud information.
  13 in total

Review 1.  Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective.

Authors:  Rudolph E Tanzi; Lars Bertram
Journal:  Cell       Date:  2005-02-25       Impact factor: 41.582

Review 2.  Beta-arrestins and cell signaling.

Authors:  Scott M DeWire; Seungkirl Ahn; Robert J Lefkowitz; Sudha K Shenoy
Journal:  Annu Rev Physiol       Date:  2007       Impact factor: 19.318

Review 3.  Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease.

Authors:  Bart De Strooper; Takeshi Iwatsubo; Michael S Wolfe
Journal:  Cold Spring Harb Perspect Med       Date:  2012-01       Impact factor: 6.915

4.  Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.

Authors:  Tong Li; Hongjin Wen; Cory Brayton; Fiona M Laird; Guojun Ma; Shiwen Peng; Lisa Placanica; T C Wu; Barbara J Crain; Donald L Price; Charles G Eberhart; Philip C Wong
Journal:  J Neurosci       Date:  2007-10-03       Impact factor: 6.167

5.  A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.

Authors:  B De Strooper; W Annaert; P Cupers; P Saftig; K Craessaerts; J S Mumm; E H Schroeter; V Schrijvers; M S Wolfe; W J Ray; A Goate; R Kopan
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

6.  beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation.

Authors:  D A Conner; M A Mathier; R M Mortensen; M Christe; S F Vatner; C E Seidman; J G Seidman
Journal:  Circ Res       Date:  1997-12       Impact factor: 17.367

Review 7.  The role of G protein-coupled receptors in the pathology of Alzheimer's disease.

Authors:  Amantha Thathiah; Bart De Strooper
Journal:  Nat Rev Neurosci       Date:  2011-02       Impact factor: 34.870

8.  Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice.

Authors:  Yasuyuki Mitani; Junko Yarimizu; Kyoko Saita; Hiroshi Uchino; Hiroki Akashiba; Yoshitsugu Shitaka; Keni Ni; Nobuya Matsuoka
Journal:  J Neurosci       Date:  2012-02-08       Impact factor: 6.167

9.  The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

Authors:  Amantha Thathiah; Kurt Spittaels; Marcel Hoffmann; Mik Staes; Adrian Cohen; Katrién Horré; Mieke Vanbrabant; Frea Coun; Veerle Baekelandt; André Delacourte; David F Fischer; Dirk Pollet; Bart De Strooper; Pascal Merchiers
Journal:  Science       Date:  2009-02-13       Impact factor: 47.728

10.  β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Authors:  Amantha Thathiah; Katrien Horré; An Snellinx; Elke Vandewyer; Yunhong Huang; Marta Ciesielska; Gerdien De Kloe; Sebastian Munck; Bart De Strooper
Journal:  Nat Med       Date:  2012-12-02       Impact factor: 53.440
View more
  6 in total

Review 1.  Sexual dimorphism in predisposition to Alzheimer's disease.

Authors:  Daniel W Fisher; David A Bennett; Hongxin Dong
Journal:  Neurobiol Aging       Date:  2018-04-17       Impact factor: 4.673

Review 2.  β-Arrestins as potential therapeutic targets for Alzheimer's disease.

Authors:  Teng Jiang; Jin-Tai Yu; Meng-Shan Tan; Xi-Chen Zhu; Lan Tan
Journal:  Mol Neurobiol       Date:  2013-05-16       Impact factor: 5.590

3.  Network Topology Analysis of Post-Mortem Brain Microarrays Identifies More Alzheimer's Related Genes and MicroRNAs and Points to Novel Routes for Fighting with the Disease.

Authors:  Sreedevi Chandrasekaran; Danail Bonchev
Journal:  PLoS One       Date:  2016-01-19       Impact factor: 3.240

4.  Homeotic Gene teashirt (tsh) has a neuroprotective function in amyloid-beta 42 mediated neurodegeneration.

Authors:  Michael T Moran; Meghana Tare; Madhuri Kango-Singh; Amit Singh
Journal:  PLoS One       Date:  2013-11-25       Impact factor: 3.240

5.  Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.

Authors:  En-Chi Hsu; Samuel K Kulp; Han-Li Huang; Huang-Ju Tu; Santosh B Salunke; Nicholas J Sullivan; Duxin Sun; Max S Wicha; Charles L Shapiro; Ching-Shih Chen
Journal:  Neoplasia       Date:  2015-06       Impact factor: 5.715

6.  Allosteric sodium binding cavity in GPR3: a novel player in modulation of Aβ production.

Authors:  Stefano Capaldi; Eda Suku; Martina Antolini; Mattia Di Giacobbe; Alejandro Giorgetti; Mario Buffelli
Journal:  Sci Rep       Date:  2018-07-23       Impact factor: 4.379
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.