| Literature DB >> 23295617 |
Frank J Hernandez1, Luiza I Hernandez, Alessandro Pinto, Thomas Schäfer, Veli C Özalp.
Abstract
Molecular gates have received considerable attention as drug delivery systems. More recently, aptamer-based gates showed great potential in overcoming major challenges associated with drug delivery by means of nanocapsules. Based on a switchable aptamer nanovalves approach, we herein report the first demonstration of an engineered single molecular gate that directs nanoparticles to cancer cells and subsequently delivers the payload in a controllable fashion.Entities:
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Year: 2013 PMID： 23295617 DOI： 10.1039/c2cc37370j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222