Literature DB >> 23295364

A two-photon fluorescent probe for amyloid-β plaques in living mice.

Cheol Ho Heo1, Kyung Ho Kim, Hyung Joong Kim, Sung Hoon Baik, Hyundong Song, Yong Soo Kim, Jeewoo Lee, Inhee Mook-jung, Hwan Myung Kim.   

Abstract

We report a small molecule two-photon probe (SAD1) that shows a significant TP action cross section (170 GM), binds to Aβ plaques specifically, readily enters the brain through the BBB, and can directly 3D monitor the individual Aβ plaque in living transgenic mice at more than 380 μm depths.

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Year:  2013        PMID： 23295364     DOI： 10.1039/c2cc38570h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Label-free imaging of amyloids using their intrinsic linear and nonlinear optical properties.

Authors:  Patrik K Johansson; Patrick Koelsch
Journal:  Biomed Opt Express       Date:  2017-01-10       Impact factor: 3.732

Review 2.  Two-photon probes for in vivo multicolor microscopy of the structure and signals of brain cells.

Authors:  Clément Ricard; Erica D Arroyo; Cynthia X He; Carlos Portera-Cailliau; Gabriel Lepousez; Marco Canepari; Daniel Fiole
Journal:  Brain Struct Funct       Date:  2018-05-11       Impact factor: 3.270

3.  Close Correlation of Monoamine Oxidase Activity with Progress of Alzheimer's Disease in Mice, Observed by in Vivo Two-Photon Imaging.

Authors:  Dokyoung Kim; Sung Hoon Baik; Seokjo Kang; Seo Won Cho; Juryang Bae; Moon-Yong Cha; Michael J Sailor; Inhee Mook-Jung; Kyo Han Ahn
Journal:  ACS Cent Sci       Date:  2016-12-07       Impact factor: 14.553

4.  A sensitive and selective electrochemical biosensor for the determination of beta-amyloid oligomer by inhibiting the peptide-triggered in situ assembly of silver nanoparticles.

Authors:  Yun Xing; Xiao-Zhen Feng; Lipeng Zhang; Jiating Hou; Guo-Cheng Han; Zhencheng Chen
Journal:  Int J Nanomedicine       Date:  2017-04-18

5.  A quadrupolar two-photon fluorescent probe for in vivo imaging of amyloid-β plaques.

Authors:  Cheol Ho Heo; Avik Ranjan Sarkar; Sung Hoon Baik; Tae Sung Jung; Jeong Jin Kim; Hyuk Kang; Inhee Mook-Jung; Hwan Myung Kim
Journal:  Chem Sci       Date:  2016-04-07       Impact factor: 9.825

Review 6.  Optical Imaging of Beta-Amyloid Plaques in Alzheimer's Disease.

Authors:  Ziyi Luo; Hao Xu; Liwei Liu; Tymish Y Ohulchanskyy; Junle Qu
Journal:  Biosensors (Basel)       Date:  2021-07-29

7.  Picomolar-sensitive β-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulated π-elongated dioxaborine-dyes.

Authors:  Jusung An; Peter Verwilst; Hira Aziz; Jinwoo Shin; Sungsu Lim; Ilwha Kim; Yun Kyung Kim; Jong Seung Kim
Journal:  Bioact Mater       Date:  2021-11-09

8.  Sensing Performance Investigations on Two-Photon Fluorescent Probes for Detecting β-Amyloid in Alzheimer's Disease.

Authors:  Yujin Zhang; Ni Luan; Kan Li; Jiancai Leng; Wei Hu
Journal:  Sensors (Basel)       Date:  2020-03-22       Impact factor: 3.576
  8 in total

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